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Logo of jnnpsycJournal of Neurology, Neurosurgery and PsychiatryCurrent TOCInstructions for authors
J Neurol Neurosurg Psychiatry. Jan 1988; 51(1): 1–9.
PMCID: PMC1032706

Cortical auditory disorders: clinical and psychoacoustic features.


The symptoms of two patients with bilateral cortical auditory lesions evolved from cortical deafness to other auditory syndromes: generalised auditory agnosia, amusia and/or pure word deafness, and a residual impairment of temporal sequencing. On investigation, both had dysacusis, absent middle latency evoked responses, acoustic errors in sound recognition and matching, inconsistent auditory behaviours, and similarly disturbed psychoacoustic discrimination tasks. These findings indicate that the different clinical syndromes caused by cortical auditory lesions form a spectrum of related auditory processing disorders. Differences between syndromes may depend on the degree of involvement of a primary cortical processing system, the more diffuse accessory system, and possibly the efferent auditory system.

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Selected References

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  • Graham J, Greenwood R, Lecky B. Cortical deafness--a case report and review of the literature. J Neurol Sci. 1980 Oct;48(1):35–49. [PubMed]
  • Ulrich G. Interhemispheric functional relationships in auditory agnosia. An analysis of the preconditions and a conceptual model. Brain Lang. 1978 May;5(3):286–300. [PubMed]
  • Oppenheimer DR, Newcombe F. Clinical and anatomic findings in a case of auditory agnosia. Arch Neurol. 1978 Nov;35(11):712–719. [PubMed]
  • Leicester J. Central deafness and subcortical motor aphasia. Brain Lang. 1980 Jul;10(2):224–242. [PubMed]
  • Goldstein MN, Brown M, Hollander J. Auditory agnosia and cortical deafness: analysis of a case with three-year followup. Brain Lang. 1975 Jul;2(3):324–332. [PubMed]
  • Miceli G. The processing of speech sounds in a patient with cortical auditory disorder. Neuropsychologia. 1982;20(1):5–20. [PubMed]
  • Buchman AS, Garron DC, Trost-Cardamone JE, Wichter MD, Schwartz M. Word deafness: one hundred years later. J Neurol Neurosurg Psychiatry. 1986 May;49(5):489–499. [PMC free article] [PubMed]
  • Auerbach SH, Allard T, Naeser M, Alexander MP, Albert ML. Pure word deafness. Analysis of a case with bilateral lesions and a defect at the prephonemic level. Brain. 1982 Jun;105(Pt 2):271–300. [PubMed]
  • Albert ML, Bear D. Time to understand. A case study of word deafness with reference to the role of time in auditory comprehension. Brain. 1974 Jun;97(2):373–384. [PubMed]
  • Vignolo LA. Auditory agnosia. Philos Trans R Soc Lond B Biol Sci. 1982 Jun 25;298(1089):49–57. [PubMed]
  • Tabira T, Tsuji S, Nagashima T, Nakajima T, Kuroiwa Y. Cortical deafness in multiple sclerosis. J Neurol Neurosurg Psychiatry. 1981 May;44(5):433–436. [PMC free article] [PubMed]
  • WOHLFART G, LINDGREN A, JERNELIUS B. Clinical picture and morbid anatomy in a case of pure word deafness. J Nerv Ment Dis. 1952 Dec;116(6):818–827. [PubMed]
  • KLEIN R, HARPER J. The problem of agnosia in the light of a case of pure word deafness. J Ment Sci. 1956 Jan;102(426):112–120. [PubMed]
  • Baker AB. [A tribute to Russell DeJong, founding Editor-in-chief]. Neurology. 1977 Jan;27(1):1–2. [PubMed]
  • Albert ML, Sparks R, Von Stockert T, Sax D. A case study of auditory agnosia: linguistic and non-linguistic processing. Cortex. 1972 Dec;8(4):427–443. [PubMed]
  • REINHOLD M. A case of auditory agnosia. Brain. 1950 Jun;73(2):203–223. [PubMed]
  • Parving A, Salomon G, Elberling C, Larsen B, Lassen NA. Middle components of the auditory evoked response in bilateral temporal lobe lesions. Report on a patient with auditory agnosia. Scand Audiol. 1980;9(3):161–167. [PubMed]
  • MASPETIOL R, MESSIMY R, SEMETTE D. [A case of central deafness]. Ann Otolaryngol. 1959 Dec;76:1103–1105. [PubMed]
  • Woods DL, Knight RT, Neville HJ. Bitemporal lesions dissociate auditory evoked potentials and perception. Electroencephalogr Clin Neurophysiol. 1984 Mar;57(3):208–220. [PubMed]
  • Michel F, Peronnet F, Schott B. A case of cortical deafness: clinical and electrophysiological data. Brain Lang. 1980 Jul;10(2):367–377. [PubMed]
  • Shindo M, Kaga K, Tanaka Y. [Auditory agnosia following bilateral temporal lobe lesions-report of a case (author's transl)]. No To Shinkei. 1981 Feb;33(2):139–147. [PubMed]
  • Lechevalier B, Rossa Y, Eustache F, Schupp C, Boner L, Bazin C. Un cas de surdité corticale épargnant en partie la musique. Rev Neurol (Paris) 1984;140(3):190–201. [PubMed]
  • Marshall RC, Rappaport BZ, Garcia-Bunuel L. Self-monitoring behavior in a case of severe auditory agnosia with aphasia. Brain Lang. 1985 Mar;24(2):297–313. [PubMed]
  • Motomura N, Yamadori A, Mori E, Tamaru F. Auditory agnosia. Analysis of a case with bilateral subcortical lesions. Brain. 1986 Jun;109(Pt 3):379–391. [PubMed]
  • Assal G, Despland PA. Présentation d'un cas d'agnosie auditive. Rev Otoneuroophtalmol. 1973 Jul-Sep;45(4):353–355. [PubMed]
  • Metz-Lutz MN, North P, Dufour P, Eber AM, Gentine A, Rohmer F. Troubles auditifs d'origine corticale. A propos de deux cas. Rev Otoneuroophtalmol. 1980 May-Jun;52(3):231–238. [PubMed]
  • ZIEGLER DK. Word deafness and Wernicke's aphasia; report of cases and discussion of the syndrome. AMA Arch Neurol Psychiatry. 1952 Mar;67(3):323–331. [PubMed]
  • Ulrich G. Das syndrom der akustischen Agnosie. Fallbericht und Versuch einer neuropsychologischen Qualifizierung. Arch Psychiatr Nervenkr. 1977 Nov 7;224(3):221–233. [PubMed]
  • Kanshepolsky J, Kelley JJ, Waggener JD. A cortical auditory disorder. Clinical, audiologic and pathologic aspects. Neurology. 1973 Jul;23(7):699–705. [PubMed]
  • Jerger J, Lovering L, Wertz M. Auditory disorder following bilateral temporal lobe insult: report of a case. J Speech Hear Disord. 1972 Nov;37(4):523–535. [PubMed]
  • Chocholle R, Chedru F, Botte MC, Chain F, Lhermitte F. Etude psychoacoustique d'un cas de "surdité corticale". Neuropsychologia. 1975 Apr;13(2):163–172. [PubMed]
  • Adams AE, Rosenberger K, Winter H, Zöllner C. A case of cortical deafness. Arch Psychiatr Nervenkr. 1977 Nov 7;224(3):213–220. [PubMed]
  • Lassen NA, Larsen B. Cortical activity in the left and right hemispheres during language-related brain functions. Phonetica. 1980;37(1-2):27–37. [PubMed]
  • LEMOYNE J, MAHOUDEAU D. A propos d'un cas d'agnosie auditive pure avec surdité corticale associée à une dysphonie fonctionnelle; observation anatomo-clinique. Ann Otolaryngol. 1959 Apr-May;76(4-5):293–310. [PubMed]
  • Gazzaniga MS, Glass AV, Sarno MT, Posner JB. Pure word deafness and hemispheric dynamics: a case history. Cortex. 1973 Mar;9(1):136–143. [PubMed]
  • Nagafuchi M, Suzuki J. Auditory agnosia due to incision of splenium corporis callosi. Acta Otolaryngol. 1973 Aug-Sep;76(2):109–113. [PubMed]
  • Celesia GG. Organization of auditory cortical areas in man. Brain. 1976 Sep;99(3):403–414. [PubMed]
  • Coslett HB, Brashear HR, Heilman KM. Pure word deafness after bilateral primary auditory cortex infarcts. Neurology. 1984 Mar;34(3):347–352. [PubMed]

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