• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of archdischArchives of Disease in ChildhoodInstructions for authorsCurrent TOC
Arch Dis Child. Jul 1994; 71(1): 3–7.
PMCID: PMC1029901

Death in infancy from unrecognised congenital heart disease.

Abstract

This study was undertaken to identify all congenital heart disease in infancy, including deaths before diagnosis, to provide a truer picture of the spectrum of congenital heart disease and to assess the 'treatability' of those dying before diagnosis. All births, infant deaths, and surviving babies with congenital heart disease in one health region in 1985-90 were identified and were classified as 'complex', 'significant', or 'minor'. Of the 1074 infants diagnosed in infancy, 185 died and 56 of these (30%) died undiagnosed. Severe non-cardiac malformations were present in 29 of the 56 while 27 were otherwise normal. Cardiovascular abnormalities in the latter group were complex in 13/27 and significant in 14/27. Identification of undiagnosed cardiovascular anomalies will improve epidemiological evaluation of congenital heart disease and, more importantly, earlier recognition of treatable abnormalities may reduce mortality.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (957K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.
 
 

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Rubin JD, Ferencz C, Brenner JI, Neill CA, Perry LW. Early detection of congenital cardiovascular malformations in infancy. Am J Dis Child. 1987 Nov;141(11):1218–1220. [PubMed]
  • Ferencz C. On the birth prevalence of congenital heart disease. J Am Coll Cardiol. 1990 Dec;16(7):1701–1702. [PubMed]
  • Samánek M, Slavík Z, Zborilová B, Hrobonová V, Vorísková M, Skovránek J. Prevalence, treatment, and outcome of heart disease in live-born children: a prospective analysis of 91,823 live-born children. Pediatr Cardiol. 1989 Fall;10(4):205–211. [PubMed]
  • Grabitz RG, Joffres MR, Collins-Nakai RL. Congenital heart disease: incidence in the first year of life. The Alberta Heritage Pediatric Cardiology Program. Am J Epidemiol. 1988 Aug;128(2):381–388. [PubMed]
  • Samánek M, Goetzová J, Benesová D. Causes of death in neonates born with a heart malformation. Int J Cardiol. 1986 Apr;11(1):63–74. [PubMed]
  • Vesterby A, Nielsen K, Borg L, Paulsen S, Baandrup U. Congenital heart malformations in Jutland, Denmark: a three year necropsy study in children aged 0-14 years. Epidemiology and classification according to sequential segmental analysis. Br Heart J. 1987 Dec;58(6):653–658. [PMC free article] [PubMed]
  • Martin GR, Perry LW, Ferencz C. Increased prevalence of ventricular septal defect: epidemic or improved diagnosis. Pediatrics. 1989 Feb;83(2):200–203. [PubMed]
  • Ferencz C, Rubin JD, McCarter RJ, Brenner JI, Neill CA, Perry LW, Hepner SI, Downing JW. Congenital heart disease: prevalence at livebirth. The Baltimore-Washington Infant Study. Am J Epidemiol. 1985 Jan;121(1):31–36. [PubMed]
  • Allen HD, Taubert KA, Deckelbaum RJ, Driscoll D, Dunnigan A, Gidding SS, Herndon P, Kavey RE, Mullins C, Snider AR, et al. Poverty and cardiac disease in children. Am J Dis Child. 1991 May;145(5):550–553. [PubMed]
  • Report of the New England Regional Infant Cardiac Program. Pediatrics. 1980 Feb;65(2 Pt 2):375–461. [PubMed]
  • Hoffman JI, Christianson R. Congenital heart disease in a cohort of 19,502 births with long-term follow-up. Am J Cardiol. 1978 Oct;42(4):641–647. [PubMed]
  • Dickinson DF, Arnold R, Wilkinson JL. Congenital heart disease among 160 480 liveborn children in Liverpool 1960 to 1969. Implications for surgical treatment. Br Heart J. 1981 Jul;46(1):55–62. [PMC free article] [PubMed]
  • Fixler DE, Pastor P, Chamberlin M, Sigman E, Eifler CW. Trends in congenital heart disease in Dallas County births. 1971-1984. Circulation. 1990 Jan;81(1):137–142. [PubMed]
  • Ferencz C, Neill CA, Boughman JA, Rubin JD, Brenner JI, Perry LW. Congenital cardiovascular malformations associated with chromosome abnormalities: an epidemiologic study. J Pediatr. 1989 Jan;114(1):79–86. [PubMed]
  • Tubman TR, Shields MD, Craig BG, Mulholland HC, Nevin NC. Congenital heart disease in Down's syndrome: two year prospective early screening study. BMJ. 1991 Jun 15;302(6790):1425–1427. [PMC free article] [PubMed]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Group

Formats:

Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...

Links

  • MedGen
    MedGen
    Related information in MedGen
  • PubMed
    PubMed
    PubMed citations for these articles

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...