• We are sorry, but NCBI web applications do not support your browser and may not function properly. More information
Logo of jnnpsycJournal of Neurology, Neurosurgery and PsychiatryCurrent TOCInstructions for authors
J Neurol Neurosurg Psychiatry. Apr 1986; 49(4): 362–368.
PMCID: PMC1028759

Inherited multiple meningiomas: a clinical, pathological and cytogenetic study of an affected family.


The clinical features of a family with inherited multiple meningiomas as the major manifestation of neurofibromatosis are presented. The value of noninvasive radiological screening investigations is emphasised. The results of cytogenetic and pathological studies on the family are presented and discussed with a review of the relevant literature.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.2M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Hosoi K. Meningiomas: With Special Reference to the Multiple Intracranial Type. Am J Pathol. 1930 May;6(3):245–260.7. [PMC free article] [PubMed]
  • DAVIDOFF LM, MARTIN J. Hereditary combined neurinomas and meningiomas. J Neurosurg. 1955 Jul;12(4):375–384. [PubMed]
  • ROVINE BW, MULFORD EH. Bilateral acoustic neurinomas with multiple meningiomas. Neurology. 1960 Mar;10:323–324. [PubMed]
  • GAIST G, PIAZZA G. Meningiomas in two members of the same family (with no evidence of neurofibromatosis). J Neurosurg. 1959 Jan;16(1):110–113. [PubMed]
  • Sahar A. Familial occurrence of meningiomas. Case report. J Neurosurg. 1965 Oct;23(4):444–445. [PubMed]
  • JOYNT RJ, PERRET GE. Meningiomas in a mother and daughter. Cases without evidence of neurofibromatosis. Neurology. 1961 Feb;11:164–165. [PubMed]
  • Pamphlett R, Mackenzie RA. Familial occurrence of meningioma: a case report. Clin Exp Neurol. 1981;18:169–173. [PubMed]
  • Memon MY. Multiple and familial meningiomas without evidence of neurofibromatosis. Neurosurgery. 1980 Sep;7(3):262–264. [PubMed]
  • Sedzimir CB, Frazer AK, Roberts JR. Cranial and spinal meningiomas in a pair of identical twin boys. J Neurol Neurosurg Psychiatry. 1973 Jun;36(3):368–376. [PMC free article] [PubMed]
  • Bolger GB, Stamberg J, Kirsch IR, Hollis GF, Schwarz DF, Thomas GH. Chromosome translocation t(14;22) and oncogene (c-sis) variant in a pedigree with familial meningioma. N Engl J Med. 1985 Feb 28;312(9):564–567. [PubMed]
  • Underwood JC, Dangerfield VJ, Parsons MA. Oestrogen receptor assay of cryostat sections of human breast carcinomas with simultaneous quantitative histology. J Clin Pathol. 1983 Apr;36(4):399–405. [PMC free article] [PubMed]
  • Seabright M. A rapid banding technique for human chromosomes. Lancet. 1971 Oct 30;2(7731):971–972. [PubMed]
  • Delleman JW, De Jong JG, Bleeker GM. Meningiomas in five members of a family over two generations, in one member simultaneously with acoustic neurinomas. Neurology. 1978 Jun;28(6):567–570. [PubMed]
  • Zankl H, Zang KD. Cytological and cytogenetical studies on brain tumors. 4. Identification of the missing G chromosome in human meningiomas as no. 22 by fluorescence technique. Humangenetik. 1972;14(2):167–169. [PubMed]
  • Waga S, Matsuda M, Handa H, Matsushima M, Ando K. Multiple meningiomas. Report of four cases. J Neurosurg. 1972 Sep;37(3):348–351. [PubMed]
  • Poisson M, Magdelenat H, Foncin JF, Bleibel JM, Philippon J, Pertuiset B, Buge A. Récepteurs d'oestrogènes et de progestérone dans les méningiomes. Etude de 22 cas. Rev Neurol (Paris) 1980;136(3):193–203. [PubMed]
  • Markwalder TM, Zava DT, Goldhirsch A, Markwalder RV. Estrogen and progesterone receptors in meningiomas in relation to clinical and pathologic features. Surg Neurol. 1983 Jul;20(1):42–47. [PubMed]
  • Cahill DW, Bashirelahi N, Solomon LW, Dalton T, Salcman M, Ducker TB. Estrogen and progesterone receptors in meningiomas. J Neurosurg. 1984 May;60(5):985–993. [PubMed]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Group


Related citations in PubMed

See reviews...See all...

Cited by other articles in PMC

See all...


  • Compound
    PubChem Compound links
  • MedGen
    Related information in MedGen
  • PubMed
    PubMed citations for these articles
  • Substance
    PubChem Substance links

Recent Activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...