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Logo of annrheumdAnnals of the Rheumatic DiseasesCurrent TOCInstructions for authors
Ann Rheum Dis. Aug 1989; 48(8): 628–631.
PMCID: PMC1003836

Pathogenesis of square bodies in ankylosing spondylitis.

Abstract

The pathogenesis of squaring of the vertebral bodies is analysed in a 25 year old patient with ankylosing spondylitis. The squaring derives from a straightening of the anterior contour. The disease was diagnosed five years before the patient's death. The remodelling of bone that explains squaring of the vertebral bodies is described for the first time. Histologically, an acute and chronic spondylitis with destruction and simultaneous rebuilding of the cortex and the spongiosa of the vertebral bodies has been found. The development of square vertebral bodies is shown to be based on a combination of a destructive osteitis and repair.

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Selected References

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  • ROMANUS R, YDEN S. Destructive and ossifying spondylitic changes in rheumatoid ankylosing spondylitis (pelvo-spondylitis ossificans). Acta Orthop Scand. 1952;22(2):88–99. [PubMed]
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  • Cawley MI, Chalmers TM, Kellgren JH, Ball J. Destructive lesions of vertebral bodies in ankylosing spondylitis. Ann Rheum Dis. 1972 Sep;31(5):345–358. [PMC free article] [PubMed]
  • Aufdermaur M, Spycher M. Pathogenesis of osteochondrosis juvenilis Scheuermann. J Orthop Res. 1986;4(4):452–457. [PubMed]

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