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West J Med. Sep 1991; 155(3): 256–259.
PMCID: PMC1002979

Leg symptoms in outpatient veterans.

Abstract

In a survey of outpatients at the Denver Veterans Affairs Medical Center for common leg symptoms--515 questionnaires returned in a 3-week period--56% reported nocturnal leg cramps, 29% reported the restless leg syndrome, and 49% reported symptoms of peripheral neuropathy. Only 33% of patients had no symptoms relating to their legs. Patients often did not report these symptoms to their physician but were more likely to do so if the symptoms were frequent. Conditions especially related to leg symptoms were hypertension, peripheral vascular disease, coronary artery disease, cerebrovascular disease, kidney disease, and hypokalemia. Most patients did not receive effective therapy for these symptoms.

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Selected References

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  • Layzer RB, Rowland LP. Cramps. N Engl J Med. 1971 Jul 1;285(1):31–40. [PubMed]
  • Joekes AM. Cramp: a review. J R Soc Med. 1982 Jul;75(7):546–549. [PMC free article] [PubMed]
  • Stewart WK, Fleming LW, Manuel MA. Muscle cramps during maintenance haemodialysis. Lancet. 1972 May 13;1(7759):1049–1051. [PubMed]
  • Whiteley AM. Cramps, stiffness and restless legs. Practitioner. 1982 Jun;226(1368):1085–1087. [PubMed]
  • Keidar S, Binenboim C, Palant A. Muscle cramps during treatment with nifedipine. Br Med J (Clin Res Ed) 1982 Oct 30;285(6350):1241–1242. [PMC free article] [PubMed]
  • Daniell HW. Simple cure for nocturnal leg cramps. N Engl J Med. 1979 Jul 26;301(4):216–216. [PubMed]
  • Weiner IH, Weiner HL. Nocturnal leg muscle cramps. JAMA. 1980 Nov 21;244(20):2332–2333. [PubMed]
  • Jones K, Castleden CM. A double-blind comparison of quinine sulphate and placebo in muscle cramps. Age Ageing. 1983 May;12(2):155–158. [PubMed]
  • Fung MC, Holbrook JH. Placebo-controlled trial of quinine therapy for nocturnal leg cramps. West J Med. 1989 Jul;151(1):42–44. [PMC free article] [PubMed]
  • Kaji DM, Ackad A, Nottage WG, Stein RM. Prevention of muscle cramps in haemodialysis patients by quinine sulphate. Lancet. 1976 Jul 10;2(7976):66–67. [PubMed]
  • Lim SH. Randomised double-blind trial of quinine sulphate for nocturnal leg cramp. Br J Clin Pract. 1986 Nov;40(11):462–462. [PubMed]
  • Baltodano N, Gallo BV, Weidler DJ. Verapamil vs quinine in recumbent nocturnal leg cramps in the elderly. Arch Intern Med. 1988 Sep;148(9):1969–1970. [PubMed]
  • Ayres S, Jr, Mihan R. Nocturnal leg cramps (systremma): a progress report on response to vitamin E. South Med J. 1974 Nov;67(11):1308–1312. [PubMed]
  • EKBOM KA. Restless legs syndrome. Neurology. 1960 Sep;10:868–873. [PubMed]
  • Fox GN. Restless legs syndrome. Am Fam Physician. 1986 Jan;33(1):147–152. [PubMed]
  • Zorick FJ, Roth T, Hartze KM, Piccione PM, Stepanski EJ. Evaluation and diagnosis of persistent insomnia. Am J Psychiatry. 1981 Jun;138(6):769–773. [PubMed]
  • Braude W, Barnes T. Clonazepam: effective treatment for restless legs syndrome in uraemia. Br Med J (Clin Res Ed) 1982 Feb 13;284(6314):510–510. [PMC free article] [PubMed]
  • Read DJ, Feest TG, Nassim MA. Clonazepam: effective treatment for restless legs syndrome in uraemia. Br Med J (Clin Res Ed) 1981 Oct 3;283(6296):885–886. [PMC free article] [PubMed]
  • Bernick C, Stern LZ. Restless legs syndrome. West J Med. 1986 Aug;145(2):263–265. [PMC free article] [PubMed]
  • Gibb WR, Lees AJ. The restless legs syndrome. Postgrad Med J. 1986 May;62(727):329–333. [PMC free article] [PubMed]
  • Telstad W, Sørensen O, Larsen S, Lillevold PE, Stensrud P, Nyberg-Hansen R. Treatment of the restless legs syndrome with carbamazepine: a double blind study. Br Med J (Clin Res Ed) 1984 Feb 11;288(6415):444–446. [PMC free article] [PubMed]
  • Handwerker JV, Jr, Palmer RF. Clonidine in the treatment of "restless leg" syndrome. N Engl J Med. 1985 Nov 7;313(19):1228–1229. [PubMed]
  • Akpinar S. Restless legs syndrome treatment with dopaminergic drugs. Clin Neuropharmacol. 1987;10(1):69–79. [PubMed]
  • Krueger BR. Restless legs syndrome and periodic movements of sleep. Mayo Clin Proc. 1990 Jul;65(7):999–1006. [PubMed]
  • Huang CY. Peripheral neuropathy in the elderly: a clinical and electrophysiologic study. J Am Geriatr Soc. 1981 Feb;29(2):49–54. [PubMed]
  • Kaur U, Chopra JS, Prabhakar S, Radhakrishnan K. Clinical spectrum of peripheral neuropathies. Indian J Med Res. 1982 Nov;76:728–735. [PubMed]
  • Dyck PJ, Oviatt KF, Lambert EH. Intensive evaluation of referred unclassified neuropathies yields improved diagnosis. Ann Neurol. 1981 Sep;10(3):222–226. [PubMed]
  • Brown MR, Dyck PJ, McClearn GE, Sima AA, Powell HC, Porte D., Jr Central and peripheral nervous system complications. Diabetes. 1982;31(Suppl 1 Pt 2):65–70. [PubMed]
  • Saudek CD, Werns S, Reidenberg MM. Phenytoin in the treatment of diabetic symmetrical polyneuropathy. Clin Pharmacol Ther. 1977 Aug;22(2):196–199. [PubMed]
  • Badran AM, Aly MA, Sous ES. A clinical trial of carbamazepine in the symptomatic treatment of diabetic peripheral neuropathy. J Egypt Med Assoc. 1975;58(11-12):627–631. [PubMed]
  • Davis JL, Lewis SB, Gerich JE, Kaplan RA, Schultz TA, Wallin JD. Peripheral diabetic neuropathy treated with amitriptyline and fluphenazine. JAMA. 1977 Nov 21;238(21):2291–2292. [PubMed]
  • Max MB, Culnane M, Schafer SC, Gracely RH, Walther DJ, Smoller B, Dubner R. Amitriptyline relieves diabetic neuropathy pain in patients with normal or depressed mood. Neurology. 1987 Apr;37(4):589–596. [PubMed]
  • Dejgard A, Petersen P, Kastrup J. Mexiletine for treatment of chronic painful diabetic neuropathy. Lancet. 1988 Jan 2;1(8575-6):9–11. [PubMed]
  • McGee SR. Muscle cramps. Arch Intern Med. 1990 Mar;150(3):511–518. [PubMed]

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