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Journal List > Ann Rheum Dis > v.41(5); Oct 1982

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Ann Rheum Dis. 1982 October; 41(5): 486–489.
PMCID: PMC1001028
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Long-term outcome in Felty's syndrome
Carter Thorne and Murray B. Urowitz
Rheumatic Disease Unit, University of Toronto, Toronto, Canada
Wellesley Hospital, Toronto, Canada
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Abstract
Felty's syndrome has again been shown to be a severe form of systemic rheumatoid disease characterised by severe joint involvement, many extra-articular features, and a high incidence of infection. In addition we have shown that splenectomy was not protective for infections and in fact may on occasion contributed to infection. Furthermore, although most patients had an increase in white blood cell count after splenectomy, 50% of patients without splenectomy showed a similar increase in white blood cell counts at follow-up. Mortality in Felty's syndrome was high, with infection being the main cause of death.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
  • Sienknecht CW, Urowitz MB, Pruzanski W, Stein HB. Felty's syndrome. Clinical and serological analysis of 34 cases. Ann Rheum Dis. 1977 Dec;36(6):500–507. [PubMed]
  • Ruderman M, Miller LM, Pinals RS. Clinical and serologic observations on 27 patients with Felty's syndrome. Arthritis Rheum. 1968 Jun;11(3):377–384. [PubMed]
  • Barnes CG, Turnbull AL, Vernon-Roberts B. Felty's syndrome. A clinical and pathological survey of 21 patients and their response to treatment. Ann Rheum Dis. 1971 Jul;30(4):359–374. [PubMed]
  • Moore RA, Brunner CM, Sandusky WR, Leavell BS. Felty's syndrome: long-term follow-up after splenectomy. Ann Intern Med. 1971 Sep;75(3):381–385. [PubMed]
  • Spivak JL. Felty's syndrome: an analytical review. Johns Hopkins Med J. 1977 Sep;141(3):156–162. [PubMed]
  • Gordon DA, Stein JL, Broder I. The extra-articular features of rheumatoid arthritis. A systematic analysis of 127 cases. Am J Med. 1973 Apr;54(4):445–452. [PubMed]
  • Goldberg J, Pinals RS. Felty syndrome. Semin Arthritis Rheum. 1980 Aug;10(1):52–65. [PubMed]
  • Luthra HS, Hunder GG. Spontaneous remission of Felty's syndrome. Arthritis Rheum. 1975 Sep–Oct;18(5):515–517. [PubMed]
  • Logue G. Felty's syndrome: granulocyte-bound immunoglobulin G and splenectomy. Ann Intern Med. 1976 Oct;85(4):437–442. [PubMed]
  • WRIGHT CS, DOAN CA, BOURONCLE BA, ZOLLINGER RM. Direct splenic arterial and venous blood studies in the hypersplenic syndromes before and after epinephrine. Blood. 1951 Mar;6(3):195–212. [PubMed]
  • Bishop CR, Rothstein G, Ashenbrucker HE, Athens JW. Leukokinetic studies. XIV. Blood neutrophil kinetics in chronic, steady-state neutropenia. J Clin Invest. 1971 Aug;50(8):1678–1689. [PubMed]
  • Zivkovic M, Baum J. Chemotaxis of polymorphonuclear leukocytes from patients with systemic lupus erythematosus and Felty's syndrome. Immunol Commun. 1972;1(1):39–49. [PubMed]
  • Vincent PC, Levi JA, Macqueen A. The mechanism of neutropenia in Felty's syndrome. Br J Haematol. 1974 Jul;27(3):463–475. [PubMed]
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