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Select item 46614091.

ATP-binding Cassette (ABC) Transport System Solute-binding Protein-guided Identification of Novel d-Altritol and Galactitol Catabolic Pathways in Agrobacterium tumefaciens C58

Daniel J. Wichelecki, Matthew W. Vetting, Liyushang Chou, Nawar Al-Obaidi, Jason T. Bouvier, Steven C. Almo, John A. Gerlt

J Biol Chem. 2015 Nov 27; 290(48): 28963–28976. Published online 2015 Oct 15. doi: 10.1074/jbc.M115.686857

PMCID:: PMC4661409

Article PDF–2.7M

Select item 26730192.

Biological effects of hexitol and altritol-modified siRNAs targeting B-Raf

Michael Fisher, Mikhail Abramov, Arthur Van Aerschot, Jef Rozenski, Vidula Dixit, Rudy L. Juliano, Piet Herdewijn

Eur J Pharmacol. Author manuscript; available in PMC 2010 Mar 15.

Published in final edited form as: Eur J Pharmacol. 2009 Mar 15; 606(1-3): 38–44. Published online 2009 Jan 30. doi: 10.1016/j.ejphar.2009.01.030

PMCID:: PMC2673019

Article PDF–1.4M

Select item 18516373.

Inhibition of MDR1 expression with altritol-modified siRNAs

Michael Fisher, Mikhail Abramov, Arthur Van Aerschot, Dong Xu, Rudolph L. Juliano, Piet Herdewijn

Nucleic Acids Res. 2007 Feb; 35(4): 1064–1074. Published online 2007 Jan 30. doi: 10.1093/nar/gkl1126

PMCID:: PMC1851637

Article PDF–1.0M

Select item 28523444.

Crystallization and preliminary X-ray study of the d-altritol oligonucleotide GTGTACAC

Margriet Ovaere, Arthur Van Aerschot, Mikhail Abramov, Piet Herdewijn, Luc Van Meervelt

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Apr 1; 66(Pt 4): 460–462. Published online 2010 Mar 31. doi: 10.1107/S1744309110007050

PMCID:: PMC2852344

Article PDF–165K

Select item 34245805.

How does hydroxyl introduction influence the double helical structure: the stabilization of an altritol nucleic acid:ribonucleic acid duplex

Margriet Ovaere, Jiri Sponer, Judit E. Sponer, Piet Herdewijn, Luc Van Meervelt

Nucleic Acids Res. 2012 Aug; 40(15): 7573–7583. Published online 2012 May 24. doi: 10.1093/nar/gks470

PMCID:: PMC3424580

Article PDF–14M

Select item 62895696.

Random-sequence genetic oligomer pools display an innate potential for ligation and recombination

Hannes Mutschler, Alexander I Taylor, Benjamin T Porebski, Alice Lightowlers, Gillian Houlihan, Mikhail Abramov, Piet Herdewijn, Philipp Holliger

eLife. 2018; 7: e43022. Published online 2018 Nov 21. doi: 10.7554/eLife.43022

PMCID:: PMC6289569

Article PDF–2.4M

Select item 71926277.

Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc–siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5′-exonuclease

Pawan Kumar, Rohan Degaonkar, Dale C Guenther, Mikhail Abramov, Guy Schepers, Marie Capobianco, Yongfeng Jiang, Joel Harp, Charalambos Kaittanis, Maja M Janas, Adam Castoreno, Ivan Zlatev, Mark K Schlegel, Piet Herdewijn, Martin Egli, Muthiah Manoharan

Nucleic Acids Res. 2020 May 7; 48(8): 4028–4040. Published online 2020 Mar 14. doi: 10.1093/nar/gkaa125

PMCID:: PMC7192627

Article PDF–3.1M

Select item 602158.

Improved hybridisation potential of oligonucleotides comprising O-methylated anhydrohexitol nucleoside congeners

A. Van Aerschot, M. Meldgaard, G. Schepers, F. Volders, J. Rozenski, R. Busson, P. Herdewijn

Nucleic Acids Res. 2001 Oct 15; 29(20): 4187–4194. doi: 10.1093/nar/29.20.4187

PMCID:: PMC60215

Article PDF–175K

Select item 11442859.

Inositol trisphosphates in carbachol-stimulated rat parotid glands.

R F Irvine, A J Letcher, D J Lander, C P Downes

Biochem J. 1984 Oct 1; 223(1): 237–243. doi: 10.1042/bj2230237

PMCID:: PMC1144285

Summary Page Browse PDF–1.0M

Select item 121916310.

Substrate specificity of sheep liver sorbitol dehydrogenase.

R I Lindstad, P Köll, J S McKinley-McKee

Biochem J. 1998 Feb 15; 330(Pt 1): 479–487. doi: 10.1042/bj3300479

Correction in:: Biochem J, volume 333 on page 847

PMCID:: PMC1219163

Summary PDF–409K

Select item 310943911.

Inhibition of hepatitis B virus replication in vivo using lipoplexes containing altritol-modified antiviral siRNAs

Justin Hean, Carol Crowther, Abdullah Ely, Rafique ul Islam, Samantha Barichievy, Kristie Bloom, Marc S Weinberg, Willem AL van Otterlo, Charles B de Koning, Felix Salazar, Patricia Marion, Eric B Roesch, Marc LeMaitre, Piet Herdewijn, Patrick Arbuthnot

Artif DNA PNA XNA. 2010 Jul-Sep; 1(1): 17–26. doi: 10.4161/adna.1.1.11981

PMCID:: PMC3109439

Article PDF–3.0M

Select item 29380112.

Biosynthesis and catabolism of 6-deoxy L-talitol by Klebsiella aerogenes mutants.

E J St Martin, R P Mortlock

J Bacteriol. 1980 Mar; 141(3): 1157–1162. doi: 10.1128/jb.141.3.1157-1162.1980

PMCID:: PMC293801

Summary Page Browse PDF–989K

Select item 386927113.

Biosynthesis of rare hexoses using microorganisms and related enzymes

Zijie Li, Yahui Gao, Hideki Nakanishi, Xiaodong Gao, Li Cai

Beilstein J Org Chem. 2013; 9: 2434–2445. Published online 2013 Nov 12. doi: 10.3762/bjoc.9.281

PMCID:: PMC3869271

Article PDF–758K

Select item 711628714.

Discovery and evolution of RNA and XNA reverse transcriptase function and fidelity

Gillian Houlihan, Sebastian Arangundy-Franklin, Benjamin T. Porebski, Nithya Subramanian, Alexander I. Taylor, Philipp Holliger

Nat Chem. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Nat Chem. 2020 Aug 1; 12(8): 683–690. Published online 2020 Jul 20. doi: 10.1038/s41557-020-0502-8

PMCID:: PMC7116287

Article PDF–2.9M

Select item 127300315.

Ribose-5-Phosphate Biosynthesis in Methanocaldococcus jannaschii Occurs in the Absence of a Pentose-Phosphate Pathway

Laura L. Grochowski, Huimin Xu, Robert H. White

J Bacteriol. 2005 Nov; 187(21): 7382–7389. doi: 10.1128/JB.187.21.7382-7389.2005

PMCID:: PMC1273003

Article PDF–132K

Select item 5583016.

Reverse transcriptase incorporation of 1,5-anhydrohexitol nucleotides

Karen Vastmans, Matheus Froeyen, Luc Kerremans, Sylvie Pochet, Piet Herdewijn

Nucleic Acids Res. 2001 Aug 1; 29(15): 3154–3163. doi: 10.1093/nar/29.15.3154

PMCID:: PMC55830

Article PDF–839K

Select item 337887417.

In vivo screening of modified siRNAs for non-specific antiviral effect in a small fish model: number and localization in the strands are important

Brian Dall Schyth, Jesper Bertram Bramsen, Malgorzata Maria Pakula, Sekar Larashati, Jørgen Kjems, Jesper Wengel, Niels Lorenzen

Nucleic Acids Res. 2012 May; 40(10): 4653–4665. Published online 2012 Jan 28. doi: 10.1093/nar/gks033

PMCID:: PMC3378874

Article PDF–1.5M

Select item 755895118.

Sweet Selenium: Synthesis and Properties of Selenium-Containing Sugars and Derivatives

Francesca Mangiavacchi, Italo Franco Coelho Dias, Irene Di Lorenzo, Pawel Grzes, Martina Palomba, Ornelio Rosati, Luana Bagnoli, Francesca Marini, Claudio Santi, Eder Joao Lenardao, Luca Sancineto

Pharmaceuticals (Basel) 2020 Sep; 13(9): 211. Published online 2020 Aug 26. doi: 10.3390/ph13090211