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1.
Figure

Figure. From: Epidemiology of Uninvestigated and Functional Dyspepsia in Asia: Facts and Fiction.

It shows the prevalence of uninvestigated dyspepsia, functional dyspepsia and seroprevalence of Helicobacter pylori infection in different Asian countries. Both population-based studies and institutional studies were included. UD, uninvestigated dyspepsia; FD, functional dyspepsia; Hp, Helicobacter pylori. For references, refer to Tables 1 and 2.

Uday C Ghoshal, et al. J Neurogastroenterol Motil. 2011 July;17(3):235-244.
2.
Figure 2

Figure 2 . From: Altered vagal and intestinal mechanosensory function in chronic unexplained dyspepsia.

Pressure at first perception (A) and maximal tolerated pain (B). First perception: functional dyspepsia versus controls, p<0.02; Billroth I gastrectomy versus functional dyspepsia, p<0.05. Maximal tolerated distension: functional dyspepsia versus controls, p<0.05; Billroth I gastrectomy versus controls, p<0.05.

G Holtmann, et al. Gut. 1998 April;42(4):501-506.
3.
Figure 1.

Figure 1. From: Evaluation And Management Of Dyspepsia – Current Perspectives.

Dyspepsia and functional dyspepsia – Rome III definitions 2006

KL Goh. Malays Fam Physician. 2007;2(1):2-7.
4.
Figure 1

Figure 1. From: Epidemiology of functional dyspepsia: A global perspective.

Global prevalence of uninvestigated dyspepsia and functional dyspepsia*.

Sanjiv Mahadeva, et al. World J Gastroenterol. 2006 May 7;12(17):2661-2666.
5.

Figure. From: Dyspepsia and Helicobacter pylori .

NICE guidance on managing uninvestigated dyspepsia (adapted from Managing dyspepsia in adults in primary care 7)

Rupal Shah. BMJ. 2007 January 6;334(7583):41-43.
6.
Figure 1

Figure 1 . From: Natural history of dyspepsia.

Percentage of responders in a population based study reporting dyspepsia, dyspepsia subgroups, and irritable bowel syndrome (IBS).12The prevalence of "overall" dyspepsia includes reflux symptoms and is given with and without concomitant IBS symptoms.

L Agreus. Gut. 2002 May;50(Suppl 4):iv2-iv9.
7.
<b>Figure 2</b>

Figure 2. From: Fundal dysaccommodation in functional dyspepsia: head-to-head comparison between the barostat and three-dimensional ultrasonographic technique.

 Mean intragastric bag volume in patients with functional dyspepsia (squares) and in healthy subjects (circles). Ingestion of the meal induces a rapid and sustained increase in intragastric bag volume in both functional dyspepsia and healthy subjects. However, in functional dyspepsia there is a significantly smaller bag volume than in healthy subjects (analysis of variance p = 0.001).

M W Mundt, et al. Gut. 2006 December;55(12):1725-1730.
8.
Figure 1

Figure 1. From: Adherence to best practice guidelines in dyspepsia: a survey comparing dyspepsia experts, community gastroenterologists and primary-care providers.

Abdominal Regions Marked & Shaded by Proportion Endorsing as part of “Dyspepsia” Definition. The survey included a regional map of the abdomen, and asked respondents to endorse areas that comport with their definition of “dyspepsia”.

B. M. R. Spiegel, et al. Aliment Pharmacol Ther. ;29(8):871-881.
9.
Figure 2  

Figure 2  . From: Differences in gastric mechanosensory function after repeated ramp distensions in non-consulters with dyspepsia and healthy controls.

Sensory thresholds for first perception (mm Hg) in controls and in those with a history of dyspepsia. *p<0.05 dyspepsia v controls.

G Holtmann, et al. Gut. 2000 September;47(3):332-336.
10.
Figure 1

Figure 1. From: A New Approach to the Management of Uninvestigated Dyspepsia in Primary Care.

Algorithm of management dyspepsia

Nizama Salihefendic, et al. Med Arch. 2015 April;69(2):133-134.
11.
Figure 1

Figure 1. From: Prevalence and characteristics of dyspepsia among college students in Zhejiang Province.

Overlaps in the prevalence of uninvestigated dyspepsia, irritable bowel syndrome and gastroesophageal reflux disease among the 1870 students surveyed from the Zhejiang Province. GERD: Gastroesophageal reflux disease; UD: Uninvestigated dyspepsia; IBS: Irritable bowel syndrome.

Meng Li, et al. World J Gastroenterol. 2014 April 7;20(13):3649-3654.
12.
Figure 1

Figure 1. From: Rate and yield of repeat upper endoscopy in patients with dyspepsia.

Study population. Starting with all esophagogastroduodenoscopies (EGDs) performed at the study sites during the study period, all EGDs with dyspepsia as an indication were identified, and patients who had undergone at least 2 EGDs with dyspepsia as an indication were selected.

Uri Ladabaum, et al. World J Gastroenterol. 2010 May 28;16(20):2520-2525.
13.
Figure

Figure. From: Implications of dyspepsia for the NHS.

Symptoms of dyspepsia reported by UK adults over the previous year

Richard Logan, et al. BMJ. 2001 September 22;323(7314):675-677.
14.
Figure 1.

Figure 1. From: Managing Dyspepsia in a Primary Care Setting.

Algorithm for the management of uninvestigated dyspepsia.

A. Kenneth Musana, et al. Clin Med Res. 2006 December;4(4):337-342.
15.
Figure

Figure. From: Implications of dyspepsia for the NHS.

Dyspepsia is not new and has been known throughout history (Indigestion by Cruickshank (1792-1872))

Richard Logan, et al. BMJ. 2001 September 22;323(7314):675-677.
16.
Figure 3.

Figure 3. From: Functional dyspepsia.

Management of functional dyspepsia. PPI, proton-pump inhibitors; SSRIs, selective serotonin-reuptake inhibitors.

Rita Brun, et al. Therap Adv Gastroenterol. 2010 May;3(3):145-164.
17.
Figure 2  

Figure 2  . From: Functional dyspepsia--a conceptual framework.

Vicious cycle in functional dyspepsia.

A Berstad. Gut. 2000 December;47(Suppl 4):iv3-iv4.
18.
Figure 2.

Figure 2. From: Functional dyspepsia.

Pathophysiologic mechanisms in functional dyspepsia. H+, acid exposure.

Rita Brun, et al. Therap Adv Gastroenterol. 2010 May;3(3):145-164.
19.
<b>Figure 1</b>

Figure 1. From: Fundal dysaccommodation in functional dyspepsia: head-to-head comparison between the barostat and three-dimensional ultrasonographic technique.

 Three‐dimensional ultrasonographic images showing an example of the stomach of a healthy subject (left) and a patient with functional dyspepsia (right). Note the larger distal part and the smaller proximal part of the stomach in functional dyspepsia.

M W Mundt, et al. Gut. 2006 December;55(12):1725-1730.
20.
Figure 1

Figure 1. From: Duodenal Implications in the Pathophysiology of Functional Dyspepsia.

Duodenal implications in the pathophysiology of functional dyspepsia. CCK, cholecystokinin.

Kwang Jae Lee, et al. J Neurogastroenterol Motil. 2010 July;16(3):251-257.

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