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Results: 2

1.
FIG. 2

FIG. 2. From: Flow Cytometric Testing of Susceptibilities of Mycobacterium tuberculosis Isolates to Ethambutol, Isoniazid, and Rifampin in 24 Hours.

Susceptibility index values of 5 of the 35 clinical isolates of M. tuberculosis tested after incubation for 24 h with or without various concentrations of INH. Isolates 497 (⧫), 941 (□), 810 (▴), and 065 (○) were susceptible to 0.02, 0.20, 1.0, or 5.0 μg or more of INH/ml, respectively. Isolate 024 (∗) was resistant to all concentrations of INH tested.

Scott M. Kirk, et al. J Clin Microbiol. 1998 June;36(6):1568-1573.
2.
FIG. 1

FIG. 1. From: Flow Cytometric Testing of Susceptibilities of Mycobacterium tuberculosis Isolates to Ethambutol, Isoniazid, and Rifampin in 24 Hours.

Intensity of fluorescence versus number of events (A, C, and E) and forward angle light scatter (B, D, and F) displayed as histogram or contour plot profiles, respectively, for M. tuberculosis organisms incubated for 24 h with (E and F) or without (C and D) 5.0 μg of INH/ml and then exposed to FDA. Other controls included M. tuberculosis organisms not incubated with INH or exposed to FDA (A and B). The mean channel fluorescence (MCF) values (the mean of the logarithmic intensity of fluorescence) of M. tuberculosis organisms with or without incubation with INH and exposed to FDA were used to calculate the susceptibility indices (SI). An index value of less than 0.75 suggested that M. tuberculosis organisms hydrolyzed less FDA than the drug-free control.

Scott M. Kirk, et al. J Clin Microbiol. 1998 June;36(6):1568-1573.

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