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Results: 2

1.
Fig. 1

Fig. 1. From: Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology.

A) AD-language associated component included left inferior frontal and temporoparietal hypometabolism, B) AD-visuospatial related component 1 involved bilateral occipito-parieto-temporal hypometabolism, C) AD-visuospatial related component 2 involved right PCC/precuneus and right lateral parietal hypometabolism, and D) AD-memory associated component included predominantly bilateral inferior frontal, but also cuneus and inferior temporal, and right inferior parietal hypometabolism. Images are presented on a study-specific template in radiological convention. Supplementary Figures S1–S4 illustrate the associations with clinical groups.

Robert Laforce, et al. Neuroimage Clin. 2014;4:508-516.
2.
Fig. 2

Fig. 2. From: Parallel ICA of FDG-PET and PiB-PET in three conditions with underlying Alzheimer's pathology.

Component pair depicting an association between hypometabolism and amyloid deposition. The spatial extent of this component pair showed that increased frontal and decreased PCC/precuneus β-amyloid deposition correlated with decreased glucose metabolism in the frontal, occipital and temporal regions. Images are presented on a study-specific template in radiological convention. Abbreviations. Amyloid beta (Aβ); Alzheimer's disease (AD); default mode network (DMN); posterior cingulate cortex (PCC).

Robert Laforce, et al. Neuroimage Clin. 2014;4:508-516.

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