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2.
Figure 2

Figure 2. Valacyclovir and infant CMV acquisition.. From: Maternal Valacyclovir and Infant Cytomegalovirus Acquisition: A Randomized Controlled Trial among HIV-Infected Women.

A) Kaplan-Meier survival curves show cumulative probability of CMV DNA detection in infant dried blood spots (DBS) in all infants by randomization arm. P value for log-rank test. B) Loess curves fitted to mean CMV DNA level. HIV-infected infant CMV DNA levels are indicated by Xs, HIV-exposed uninfected infant CMV DNA levels are indicated by closed circles; black indicates placebo and red valacyclovir arm. Dotted line indicates assay limit of detection (100 copies/million cells).

Alison C. Roxby, et al. PLoS One. 2014;9(2):e87855.
3.
Figure 3

Figure 3. Valacyclovir and maternal CMV levels.. From: Maternal Valacyclovir and Infant Cytomegalovirus Acquisition: A Randomized Controlled Trial among HIV-Infected Women.

A) Loess curves fitted to mean CMV DNA levels in breast milk samples collected at 2, 6 and 14 weeks postpartum, and 6, 9 and 12 months postpartum. Red line and markers indicate women randomized to valacyclovir. Dotted line indicates assay limit of detection (100 copies/ml). Note: few women were breastfeeding after 180 days postpartum. B) Bars show proportion of women with detectable CMV DNA in the cervix at pre-randomization (34 weeks gestation) and 4 weeks post-randomization (38 weeks gestation). P values below the graph compare the proportion of detectable responses between arms, p values above graph compare the proportion of detectables within each arm, over the two time-points. C) Plots show individual CMV DNA levels for women at baseline and post-randomization, red middle bars show group medians, red whiskers show upper and lower quartiles. P values below the graph show comparison of CMV DNA levels between arms, p values above graph compare CMV DNA levels within each arm, over the two time-points.

Alison C. Roxby, et al. PLoS One. 2014;9(2):e87855.

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