Results: 2

1.
Figure 2

Figure 2. From: Characterizing the Retinoblastoma 1 locus: putative elements for Rb1 regulation by in silico analysis.

The positions of CpG islands in the Rb1 locus. The first and last blocks in the schematic gene represent the first and fourth exons of Rb1, respectively. “Bona fide” strategy accounts for a number of functional CGIs and estimates their strengths (see scores in the figure). Also, CpGProD program predicts promoter- overlapping CGIs. “Weizmann CpG islands” predicts highly conserved CGIs. Although different methods were used, the results are largely concordant.

Mohammadreza Hajjari, et al. Front Genet. 2014;5:2.
2.
Figure 1

Figure 1. From: Characterizing the Retinoblastoma 1 locus: putative elements for Rb1 regulation by in silico analysis.

Rb1 gene structure. Transcribed RNAs from this locus identified by UCSC genome browser. The exons are represented by black blocks. Different promoters and transcription start sites of Rb1 locus are shown. The diagram shows a schematic representation of results from different databases and programs which are described in the text. The yellow circles show CpG islands identified by UCSC genome browser. There are two red boxes which show the promoters identified by HMM-Promoter prediction algorithm. TSSs (Transcription start sites) are recognized by different algorithms such as CoreBoost, Eponine, and SwitchGear. LPAR is a gene within Rb1.

Mohammadreza Hajjari, et al. Front Genet. 2014;5:2.

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