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FIGURE 1. From: The role of microRNAs in regulating neuronal connectivity.

Identification of the timing mechanism for orderly AVM axon connectivity. (A) Sequential events of AVM axon outgrowth and synapse formation in the first larval (L1) stage of C. elegans. (1) Axon grows ventrally. (2) Axon grows anteriorly. (3) End of axon pathfinding and initiation of synapse formation in the nerve ring. (B) The lin-4–lin-14 regulatory circuit signals the end of axon pathfinding.

Hui Chiu, et al. Front Cell Neurosci. 2013;7:283.

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