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Figure 1.

Figure 1. From: Alcohol Intake Between Menarche and First Pregnancy: A Prospective Study of Breast Cancer Risk.

Relative risks (RRs) of breast cancer (solid diamonds) and proliferative benign breast disease (solid circles) per 10g/day alcohol consumption between menarche and first pregnancy, according to the length of duration between these events, among parous women participating in the Nurses’ Health Study II. The releative risks were adjusted for cumulative alcohol consumption after first pregnancy and other breast cancer risk factors including age (continuous), questionnaire year (continuous), current body mass index (quintiles), age at menarche (<12, 12, 13, or ≥14 years), menopausal status (premenopausal, postmenopausal, or unknown), average body size between ages 5 and 10 years (somatotype pictogram 1, 1.5–2, 2.5–3, 3.5–4.5, ≥5, or unknown), family history of breast cancer in mother or sister(s) (yes or no), postmenopausal hormone use (never use, ever use, or unknown), total duration of breastfeeding (0, 0.1–11 months, ≥12 months, or unknown), and parity and age at first pregnancy (nulliparous; 1–2 pregnancies, age at first pregnancy <25 years; 1–2 pregnancies, age at first pregnancy 25–29 years; 1–2 pregnancies, age at first pregnancy ≥30 years; ≥3 pregnancies, age at first pregnancy <25 years; ≥3 pregnancies, age at first pregnancy 25–29 years; ≥3 pregnancies, age at first pregnancy ≥30 years, or unknown).

Ying Liu, et al. J Natl Cancer Inst. 2013 October 16;105(20):1571-1578.

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