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Results: 4

1.
Figure 4

Figure 4. From: Modular reorganization of brain resting state networks and its independent validation in Alzheimer's disease patients.

Classification power (ROC curve) when both biomarkers of GMC and index A are combined.

Guangyu Chen, et al. Front Hum Neurosci. 2013;7:456.
2.
Figure 1

Figure 1. From: Modular reorganization of brain resting state networks and its independent validation in Alzheimer's disease patients.

Individual modularity values (Q) distribution of a network as the function of the number of edges and its corresponding random network. Error bar shows the standard deviation. All groups' networks have a significantly larger Q-value than the corresponding random networks. Larger Q shows the ability of a network to form modules.

Guangyu Chen, et al. Front Hum Neurosci. 2013;7:456.
3.
Figure 2

Figure 2. From: Modular reorganization of brain resting state networks and its independent validation in Alzheimer's disease patients.

Module of the non-threshold positive group networks of CN and AD at 3T. Color represents the individual community. First row of (A) and (B) is the network view, the second row of (A) and (B) shows the brain module organization overlaid in the brain template and the last row (C and D) is the module reorganization pattern between CN and AD. The label module numbers in the brain views of (A) and (B) are matched with the module numbers in (C) and (D), respectively. Two matrices, (C) and (D), show the grouped CC matrix of CN and AD. In (C) and (D), numbers along each matrix labeled the module number for each group. Red arrow and red connection lines show the reorganization pattern from CN to AD. The thickness of each line represents the number of members.

Guangyu Chen, et al. Front Hum Neurosci. 2013;7:456.
4.
Figure 3

Figure 3. From: Modular reorganization of brain resting state networks and its independent validation in Alzheimer's disease patients.

(A) and (B) Show the changes of insula module between CN (A) and AD (B); each dot is the center of an AAL-based brain region; regions with same color are in the same module, solid line means higher connection, while the dash line represents the weaker connection. (C) Two indices (index A and index B) of CN_3T and AD_3T (test groups). (D) Two indices of two young subject groups, CN_3T and MCI_3T (validation groups). (E) Two indices of CN_1.5T, MCI_1.5T, and AD_1.5T (validation groups). (F) The average of GMC of each group. (G) The two indices after removal of the GMC effect of each group; where (*) represents the significance (p < 0.05) in comparison to CN_1.5T and (**) represents the significance (p < 0.05) in comparison to the MCI group. Error bar indicates the standard deviation. (++) represents both young groups have significant larger index A value than the old CN_3T and MCI_3T groups.

Guangyu Chen, et al. Front Hum Neurosci. 2013;7:456.

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