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Results: 4

1.
Figure 1

Figure 1. From: A mixture model for expression deconvolution from RNA-seq in heterogeneous tissues.

The representative graphical model of TEMT.

Yi Li, et al. BMC Bioinformatics. 2013;14(Suppl 5):S11-S11.
2.
Figure 3

Figure 3. From: A mixture model for expression deconvolution from RNA-seq in heterogeneous tissues.

Comparisons between indirect estimates from TEMT and direct estimates from eXpress for cell type b in terms of estimated counts. The x-axis is the estimated counts from the two models, and the y-axis is the true counts. Each point in the figure is a comparison between the estimated count and true count. The red points are the direct estimates from eXpress, while the blue points are the indirect estimates from TEMT. Figure (a)-(f) are each comparison with cell type b proportions from 40% to 90%.

Yi Li, et al. BMC Bioinformatics. 2013;14(Suppl 5):S11-S11.
3.
Figure 4

Figure 4. From: A mixture model for expression deconvolution from RNA-seq in heterogeneous tissues.

Analysis results of the ENCODE data of 6 different K562 cells proportions with the bias module disabled. The x-axis is the different K562 cells proportions, and the y-axis is the Error Fraction of the corresponding estimates. The green and blue lines are the estimates from TEMT for GM12878 and K562 cells, based on the read sets of the GM12878 cells pure sample and the mixed sample. The red line is the direct estimates from eXpress for K562 cells, based on the read set of the mixed sample.

Yi Li, et al. BMC Bioinformatics. 2013;14(Suppl 5):S11-S11.
4.
Figure 2

Figure 2. From: A mixture model for expression deconvolution from RNA-seq in heterogeneous tissues.

Analysis results of simulated data of 6 different cell type b proportions with the bias module disabled. The x-axis is the different cell type b proportion, and the y-axis is the Error Fraction of the corresponding estimates. The green and blue lines are the estimates from TEMT for cell type a and cell type b, based on the two read sets of the cell type a pure sample and the mixed sample. The yellow and magenta lines are the estimates from eXpress for cell type a and cell type b, based on the two read sets of the cell type a pure sample and the cell type b pure sample. The red line is the direct estimates from eXpress for cell type b, based on the read set of the mixed sample.

Yi Li, et al. BMC Bioinformatics. 2013;14(Suppl 5):S11-S11.

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