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Figure 3

Figure 3. Mean absolute and relative regional WML volumes for the three patterns (black columns: pattern 1, grey columns: pattern 2, white columns: pattern 3).. From: Spatial Distribution of Cerebral White Matter Lesions Predicts Progression to Mild Cognitive Impairment and Dementia.

The scales of the graphics are different for the frontal/parietal and the temporal/occipital regions. (A) Frontal and parietal absolute WML volumes. (B) Relative (in percentage) WML volumes in the frontal (frontal WMLr) and parietal regions (parietal WMLr). (C) Temporal and occipital absolute WML volumes. (D) Relative (in percentage) WML in the temporal (temporal WMLr) and occipital regions (occipital WMLr). * p <0.01 versus pattern 1 (Tukey's HSD test).† p<0.01 versus pattern 2 (Tukey's HSD test).

Marion Mortamais, et al. PLoS One. 2013;8(2):e56972.
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Figure 2

Figure 2. Decision tree (built using the data on total WML volume and on relative WML volume in the frontal, parietal, temporal and occipital regions as potential descriptors).. From: Spatial Distribution of Cerebral White Matter Lesions Predicts Progression to Mild Cognitive Impairment and Dementia.

The three distribution patterns could be used to discriminate between subjects who developed MCI/dementia and subjects who remained cognitively stable. Sensitivity: 29%, specificity: 88%, positive predictive value: 46%, negative predictive value: 78%. Temporal WMLr: (temporal WML volume/total WML volume) ×100.

Marion Mortamais, et al. PLoS One. 2013;8(2):e56972.

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