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Results: 3

1.

Figure. From: Immunogenicity and safety of different formulations of an adjuvanted glycoprotein D genital herpes vaccine in healthy adults.

Figure 3. Levels of integrated stimulation index (panel (A), interleukin-2 (panel (B), γ interferon (panel (C) by study visit in each treatment group. Group 1 = gD-2t 40 μg, Group 2 = gD-2t 80 μg, Group 3 = gD-2t 20 μg, Group 4 = gD-2t 20 μg, Group 5 = gD-2t 20 μg. ISI, integrated stimulation index; IL-2, interleukin-2; γ-IFN, gamma interferon; M, month.

Geert Leroux-Roels, et al. Hum Vaccin Immunother. 2013 June 1;9(6):1254-1262.
2.

Figure. From: Immunogenicity and safety of different formulations of an adjuvanted glycoprotein D genital herpes vaccine in healthy adults.

Figure 1. Flow diagram illustrating enrolment, randomization and follow-up of study participants. Group 1 = gD-2t 40 μg, Group 2 = gD-2t 80 μg, Group 3 = gD-2t 20 μg, Group 4 = gD-2t 20 μg, Group 5 = gD-2t 20 μg. Vaccine formulations administered to groups 1 to 4 contained phenoxyethanol preservative and those administered to group 5 contained thiomersal preservative. The vaccine formulations administered to groups 1–3 and 5 contained Al(OH)3. The vaccine formulations administered to group 4 contained AlPO4.

Geert Leroux-Roels, et al. Hum Vaccin Immunother. 2013 June 1;9(6):1254-1262.
3.

Figure. From: Immunogenicity and safety of different formulations of an adjuvanted glycoprotein D genital herpes vaccine in healthy adults.

Figure 2. Geometric mean gD specific antibodies (panel (A) and HSV neutralizing antibodies (panel (B) levels by study visit in each treatment group. Group 1 = gD-2t 40 μg, Group 2 = gD-2t 80 μg, Group 3 = gD-2t 20 μg, Group 4 = gD-2t 20 μg, Group 5 = gD-2t 20 μg. GMT, geometric mean antibody titer; CI, confidence interval; M, month.

Geert Leroux-Roels, et al. Hum Vaccin Immunother. 2013 June 1;9(6):1254-1262.

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