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Figure 1

Figure 1. From: Exome Sequencing and Genome-Wide Linkage Analysis in 17 Families Illustrates the Complex Contribution of TTN Truncating Variants to Dilated Cardiomyopathy.

Pedigrees of families with DCM. Squares represent males, circles females. Diagonal lines mark deceased individuals. Solid symbols denote DCM. Gray symbols represent any cardiovascular abnormality. Open symbols represent unaffected individuals or individuals with no data available for analysis. The presence or absence of the family’s TTN truncating variant is indicated by a + or − symbol, respectively; obligate carriers are noted in parenthesis, (+), unknown zygosity, (?). Individuals who underwent exome sequencing are denoted (exome).

Nadine Norton, et al. Circ Cardiovasc Genet. 2013 April;6(2):10.1161/CIRCGENETICS.111.000062.

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