Figure 1

Figure 1. Performance and correlation of DAS28-MCP-1 with DAS28.. From: Blood Monocyte Chemotactic Protein-1 (MCP-1) and Adapted Disease Activity Score28-MCP-1: Favorable Indicators for Rheumatoid Arthritis Activity.

Correlation analysis was performed by estimating Pearson’s correlation coefficients for 111 patients with rheumatoid arthritis, including 48 newly diagnosed (blood drawn four times in a 6-month period) patients and 63 patients undergoing standard treatment (blood drawn only once). (A) Overall correlation between DAS28-MCP-1 and DAS28 (48 newly diagnosed patients at 0 months plus 63 patients) (r  = 0.984 and P<0.001). (B) Change in DAS28-MCP-1 during a 6-month period was assessed by ANOVA and post-hoc LSD test. The P-values were <0.001, 0.022, and <0.001 for the comparison of 0 (n  = 48) months, with 1 (n  = 44), 3 (n  = 36), and 6 months (n  = 30), respectively. Values were expressed as mean ± SD. (C) Correlation between DAS28 and DAS28-MCP-1 at 0 months among newly diagnosed patients (r  = 0.944 and P<0.001). (D) Correlation between DAS28 and DAS28-MCP-1 at 1 months among newly diagnosed patients (r  = 0.951 and P<0.001). (E) Correlation between DAS28 and DAS28-MCP-1 at 3 months among newly diagnosed patients (r  = 0.862 and P<0.001). (F) Correlation between DAS28 and DAS28-MCP-1 at 6 months among newly diagnosed patients (r  = 0.865 and P<0.001).

Lieh-bang Liou, et al. PLoS One. 2013;8(1):e55346.

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