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1.
Figure 1

Figure 1. Flowchart detailing the study participation and adherence to sample submissions for diagnosis of S. mansoni.. From: The Urine Circulating Cathodic Antigen (CCA) Dipstick: A Valid Substitute for Microscopy for Mapping and Point-Of-Care Diagnosis of Intestinal Schistosomiasis.

According to single Kato-Katz thick smear examinations, the prevalence of S. mansoni in preschool children living in the high, moderate and low transmission settings was 7.2%, 16.9% and 38.8%, respectively. Study was conducted in October/November 2009 and 2010.

José Carlos Sousa-Figueiredo, et al. PLoS Negl Trop Dis. 2013 January;7(1):e2008.
2.
Figure 2

Figure 2. Prevalence of intestinal schistosomiasis in preschoolers at baseline and follow-up.. From: The Urine Circulating Cathodic Antigen (CCA) Dipstick: A Valid Substitute for Microscopy for Mapping and Point-Of-Care Diagnosis of Intestinal Schistosomiasis.

Microscopy was conducted on duplicate Kato-Katz thick smears from the same stool sample; a single CCA tests was conducted on a single urine sample; SEA-ELISAs were conducted in the field; ‘combined results’: if positive for any test then considered child as positive; and mathematical model by Jordan and colleagues (‘Triplicate stool samples microscopy’) [29] Baseline results represented in top section, and follow-up results represented in bottom section.

José Carlos Sousa-Figueiredo, et al. PLoS Negl Trop Dis. 2013 January;7(1):e2008.
3.
Figure 3

Figure 3. ROC curves of microscopy and the CCA using SEA-ELISA results as reference test.. From: The Urine Circulating Cathodic Antigen (CCA) Dipstick: A Valid Substitute for Microscopy for Mapping and Point-Of-Care Diagnosis of Intestinal Schistosomiasis.

The receiver operating characteristic (ROC) curves and the area under the curve (AUC) of faecal microscopy (A) and CCA (B) are presented from either a low (green), moderate (orange) or high transmission (red) setting. Results are presented from baseline (above) and follow-up (below) surveys.

José Carlos Sousa-Figueiredo, et al. PLoS Negl Trop Dis. 2013 January;7(1):e2008.

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