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1.
Figure 3

Figure 3. Age-stratified epidemic attack rates by scenario and assumed basic reproduction number (R0). SPR. From: H3N2v and Other Influenza Epidemic Risk Based on Age-Specific Estimates of Sero-Protection and Contact Network Interactions.

 = Sero-protection rate – defined as the proportion (%) considered sero-protected on the basis of having met or exceeded the specified antibody titre threshold; H3N2v: swine-origin H3N2 variant strain; SPR presented based on antibody levels measured in sera collected in fall 2010; SPR40: the proportion considered sero-protected according to the standard hemagglutination inhibition (HI) titre threshold of 40; ½SPR40: assumes half the individuals meeting SPR40 are considered sero-protected Overall attack rates are indicated by the horizontal line. Based on simulations using age-specific parameters, these overall attack rates were derived as the total number of infections divided by the total population size.

Danuta M. Skowronski, et al. PLoS One. 2013;8(1):e54015.
2.
Figure 1

Figure 1. Effective reproduction number (Reff) according to various scenarios of population immunity by initial basic reproduction number (R0) assumed.. From: H3N2v and Other Influenza Epidemic Risk Based on Age-Specific Estimates of Sero-Protection and Contact Network Interactions.

SPR = Sero-protection rate – defined as the proportion (%) considered sero-protected on the basis of having met or exceeded the specified antibody titre threshold; pre-H1N1pdm09: 2009 H1N1 pandemic virus; SPR presented based on PRE-pandemic antibody levels measured in 2009 or earlier; post-H1N1pdm09: 2009 H1N1 pandemic virus; SPR presented based on POST-pandemic antibody levels measured in fall 2010; H3N2v: swine-origin H3N2 variant strain; SPR presented based on antibody levels measured in sera collected in fall 2010; post-Brisbane: a contemporary seasonal human influenza H3N2 virus; SPR presented based post-circulation antibody levels in sera collected in fall 2010; SPR40: the proportion considered sero-protected according to the standard hemagglutination inhibition (HI) titre threshold of 40; ½SPR40: assumes half the individuals meeting SPR40 are considered sero-protected; SPR80: the proportion considered sero-protected according to a hemagglutination inhibition (HI) titre threshold of 80.

Danuta M. Skowronski, et al. PLoS One. 2013;8(1):e54015.
3.
Figure 2

Figure 2. Age-stratified epidemic attack rates by scenario and assumed basic reproduction number (R0 = 1.40). SPR. From: H3N2v and Other Influenza Epidemic Risk Based on Age-Specific Estimates of Sero-Protection and Contact Network Interactions.

 = Sero-protection rate – defined as the proportion (%) considered sero-protected on the basis of having met or exceeded the specified antibody titre threshold; pre-H1N1pdm09: 2009 H1N1 pandemic virus; SPR presented based on PRE-pandemic antibody levels measured in 2009 or earlier; post-H1N1pdm09: 2009 H1N1 pandemic virus; SPR presented based on POST-pandemic antibody levels measured in fall 2010; H3N2v: swine-origin H3N2 variant strain; SPR presented based on antibody levels measured in sera collected in fall 2010; post-Brisbane: a contemporary seasonal human influenza H3N2 virus; SPR presented based post-circulation antibody levels in sera collected in fall 2010; SPR40: the proportion considered sero-protected according to the standard hemagglutination inhibition (HI) titre threshold of 40; ½SPR40: assumes half the individuals meeting SPR40 are considered sero-protected; SPR80: the proportion considered sero-protected according to a hemagglutination inhibition (HI) titre threshold of 80 Overall attack rates are indicated by the horizontal line. Based on simulations using age-specific parameters, these overall attack rates were derived as the total number of infections divided by the total population size.

Danuta M. Skowronski, et al. PLoS One. 2013;8(1):e54015.

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