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Figure 1

Figure 1. Regional association results for chromosome 7 SNPs in the GLI-Kruppel family member GLI3 gene.. From: Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis.

The index, associated SNP is named and shown as a purple diamond (rs2049622: P = 8.9×10−6); remaining SNPs are colored according to the strength of LD (r2) with the index SNP (see figure legend). Pairwise LD and local recombination rates were calculated using HapMap CEU population data (Phase 2, release #22), with annotated genes mapped according to NCBI Build 36 sequence position.

Elizabeth G. Holliday, et al. PLoS One. 2013;8(1):e53830.

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