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Figure 1

Figure 1. Predicted resistance level to antiretroviral drugs in pretreated patients from the two studied cohorts.. From: High Drug Resistance Prevalence among Vertically HIV-Infected Patients Transferred from Pediatric Care to Adult Units in Spain.

Resistance level was estimated according to the HIVdb Interpretation Algorithm (Stanford University, Palo Alto, CA, USA) [19]. PI, protease inhibitors: nelfinavir (NFV), saquinavir/r (SQV/r), indinavir/r (IDV/r), atazanavir/r (ATV/r), fosamprenavir/r (FPV/r), lopinavir/r (LPV/r), tipranavir/r (TPV/r) and darunavir/r (DRV/r), where “/r” indicates co-administration with low-dose ritonavir (RTV) for pharmacological “boosting”. NRTI, nucleoside reverse transcriptase inhibitors: zidovudine (AZT), stavudine (d4T), lamivudine (3TC), emtricitabine (FTC), didanosine (DDI), abacavir (ABC), tenofovir (TDF). NNRTI, non-nucleoside reverse transcriptase inhibitors: efavirenz (EFV), nevirapine (NVP), rilpivirine (RPV), etravirine (ETR). **Statistical differences (p<0.05) in resistance levels have been found between transferred and non-transferred patients for these drugs.

Miguel de Mulder, et al. PLoS One. 2012;7(12):e52155.

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