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1.
Figure 2

Figure 2. Effects of aging and GSR on positive correlations.. From: Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity.

Frequency plots of multi-scan ICCs for significant positive correlations showed pronounced decreases in positive (Pos.) correlations with aging and GSR.

Jie Song, et al. PLoS One. 2012;7(12):e49847.
2.
Figure 1

Figure 1. Effects of aging and GSR on reliability of RSFC.. From: Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity.

Frequency plots of multi-scan ICCs for significant and reliable correlations (i.e., p-value <0.05 adjusted by FDR correction, ICC >0.5) showed pronounced decreases in significant and reliable (SigRe) correlations with aging and GSR. (Y–Young, O–Old, wGSR–with GSR, woGSR–without GSR).

Jie Song, et al. PLoS One. 2012;7(12):e49847.
3.
Figure 8

Figure 8. Effects of aging and GSR on stability of RSFC within-subject across scans.. From: Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity.

Frequency plots of Kendall’s W across scan sessions for significant correlations showed pronounced decreases in Sig. correlations with GSR. High stability of RSFC from scan to scan remains independent of aging effects.

Jie Song, et al. PLoS One. 2012;7(12):e49847.
4.
Figure 9

Figure 9. Effects of aging and GSR on stability of RSFC between-subject within scan.. From: Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity.

GSR could potentially enhance the agreement/stability across scan sessions from subject to subject. Each black dot represents Kendall’s W between subjects within each scan. Cross points represent Kendall’s W values averaged across three scans.

Jie Song, et al. PLoS One. 2012;7(12):e49847.
5.
Figure 6

Figure 6. Scatterplot of ICC for connections with vs. without GSR.. From: Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity.

GSR tends to reduce the reliability of connections (i.e., regression lines are under y = x when ICC >0.3 for the young group and ICC >0.15 for the old group). Each data point indicates a significant connection from each group. Black lines represent linear regression fits of the data and red lines represent y = x.

Jie Song, et al. PLoS One. 2012;7(12):e49847.
6.
Figure 5

Figure 5. Effects of aging and GSR on brain functional networks.. From: Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity.

Pie chart illustrates the proportion of significant and reliable functional connections within each network. Binomial proportion tests showed aging was associated with significant decreases in reliable connections between-network but increases within sensorimotor and fronto-parietal networks. Each percentage number indicates the proportion of functional connections within corresponding networks.

Jie Song, et al. PLoS One. 2012;7(12):e49847.
7.
Figure 7

Figure 7. Scan 1 vs. scan 2 vs. scan 3.. From: Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity.

Group-averaged correlations from each scan session are plotted against each other. High consistency of RSFC from scan to scan is observed independent of aging and GSR factor. Overlaid blue lines represent linear regression fits of the data points and the r-values of the fit represent Pearson correlations of the data points.

Jie Song, et al. PLoS One. 2012;7(12):e49847.
8.
Figure 4

Figure 4. Reliability of RSFC vs. magnitude of functional connections in the old group.. From: Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity.

A left shift of data points indicates a reduction in the magnitude of functional connections when GSR is applied. The Wilcoxon signed-rank test shows reduced ICC values when GSR is applied (p-value <0.0001). Each data point represents a correlation that is significant both with and without GSR. Linear regression fits were overlaid on the data.

Jie Song, et al. PLoS One. 2012;7(12):e49847.
9.
Figure 3

Figure 3. Reliability of RSFC vs. magnitude of functional connections in the young group.. From: Age-Related Differences in Test-Retest Reliability in Resting-State Brain Functional Connectivity.

A left shift of data points indicates a reduction in the magnitude of functional connections when GSR is applied. The Wilcoxon signed-rank test shows reduced ICC values when GSR is applied (p-value <0.0001). Each data point represents a correlation that is significant both with and without GSR. Linear regression fits were overlaid on the data.

Jie Song, et al. PLoS One. 2012;7(12):e49847.

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