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Figure 1

Figure 1. From: Sedation in the intensive care setting.

Empiric sedation protocol.
With permission from www.icudelirium.org
Notes: Midazolam 1–3 mg/hr gtt rarely if >2 midaz boluses/hr and propofol intolerance. *Propofol intolerance refers to propofol infusion syndrome, hemodynamic instability, increasing CPK > 5000 IU/L, triglycerides >500 mg/dl or use >96 hrs.
Abbreviations: CAM-ICU, Confusion Assessment Method for the Intensive Care Unit; Dexmed, dexmedetomidine; ETOH, ethanol; gtt, infusion; pharm, pharmacological; prn, as needed; RASS, Richmond Agitation-Sedation Scale; SAT, spontaneous awakening trial; SBT, spontaneous breathing trial

Christopher G Hughes, et al. Clin Pharmacol. 2012;4:53-63.

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