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2.
Figure 3

Figure 3. The effect of L-NAME (100 µM) on the concentration-response curves for phenylephrine in aortic rings in control (CT) conditions or HgCl2 (A,B).. From: Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery.

Results (mean±SEM) are expressed as a percentage of the response to 75 mmol/l KCl. *P<0.05 by ANOVA. Number of animals used in parentheses. (C) Differences in the area under the concentration-response curve (dAUC) for aortic rings incubated in the presence and absence of L-NAME in controls (CT) or HgCl2. *P<0.05 by Student’s t-test.

Núbia Belem Lemos, et al. PLoS One. 2012;7(11):e49005.
3.
Figure 4

Figure 4. The effect of apocynin (0.3 mM) on the concentration-response curves for phenylephrine in aortic rings in control (CT) conditions or HgCl2 (A,B).. From: Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery.

Results (mean±SEM) are expressed as a percentage of the response to 75 mmol/l KCl. *P<0.05 by ANOVA. Number of animals used in parentheses. (C) Differences in the area under the concentration-response curve (dAUC) in aortic rings cultured the presence and absence apocynin (0.3 mM), under control (CT) conditions or HgCl2. *P<0.05 by Student’s t-test.

Núbia Belem Lemos, et al. PLoS One. 2012;7(11):e49005.
4.
Figure 2

Figure 2. The effect of endothelium removal (E-) on the concentration-response curves for phenylephrine in aortic rings in control (CT) conditions or HgCl2 (A,B).. From: Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery.

Results (mean±SEM) are expressed as a percentage of the response to 75 mmol/l KCl. *P<0.05 by ANOVA. Number of animals used in parentheses. (C) Differences in area under the concentration-response curve (dAUC) in the presence and absence of the endothelium of aortic rings in control (CT) conditions or HgCl2. *P<0.05 by Student’s t-test.

Núbia Belem Lemos, et al. PLoS One. 2012;7(11):e49005.
5.
Figure 7

Figure 7. (A, B) The effect of indomethacin (Indo, 10 µM), on the concentration-response curves for phenylephrine in aortic rings in control (CT) conditions or HgCl2.. From: Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery.

Results (mean±SEM) are expressed as a percentage of the response to 75 mmol/l KCl. *P<0.05 by ANOVA. Number of animals used in parentheses. (C) Differences in the area under the concentration-response curve (dAUC) in aortic rings cultured in the presence of indomethacin (10 µM) under control (CT) conditions and after acute incubation with mercury HgCl2. *P<0.05 by Student’s t-test.

Núbia Belem Lemos, et al. PLoS One. 2012;7(11):e49005.
6.
Figure 5

Figure 5. The effect of superoxide dismutase (SOD, 150 U ml−1) on the concentration-response curves for phenylephrine in aortic rings in control (CT) conditions or HgCl2 (A,B).. From: Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery.

Results (mean±SEM) are expressed as a percentage of the response to 75 mmol/l KCl. *P<0.05 by ANOVA. Number of animals used in parentheses. (C) Differences in the area under the concentration-response curve (dAUC) in aortic rings cultured in the presence and absence of superoxide dismutase (SOD, 150 U ml−1) under control (CT) conditions or HgCl2. *P<0.05 by Student’s t-test.

Núbia Belem Lemos, et al. PLoS One. 2012;7(11):e49005.
7.
Figure 6

Figure 6. (A,B) The effects of enalapril (10 µM) and (C,D) losartan (10 µM) on the concentration-response curves for phenylephrine and (E) densitometric analysis of the western blot for AT1 in aortic rings in control (CT) conditions or HgCl2.. From: Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery.

Results (mean±SEM) are expressed as a percentage of the response to 75 mmol/l KCl. *P<0.05 by ANOVA. (E) Densitometric analysis of the western blot for angiotensin receptor 1 (AT1) protein expression in aortic rings cultured in the absence (CT) of HgCl2 and after acute incubation with HgCl2. *P<0.05 by Student’s t-test. Number of animals used in parentheses. Representative blots are also shown.

Núbia Belem Lemos, et al. PLoS One. 2012;7(11):e49005.
8.
Figure 8

Figure 8. (A,B) The effect of NS 398 (10−6 M) and (D,E) furegrelate (FU, 10−3 M) on the concentration-response curves for phenylephrine in aortic rings in control (CT) conditions or HgCl2.. From: Low Mercury Concentration Produces Vasoconstriction, Decreases Nitric Oxide Bioavailability and Increases Oxidative Stress in Rat Conductance Artery.

Results (mean±SEM) are expressed as a percentage of the response to 75 mmol/l KCl. *P<0.05 by ANOVA. Number of animals used in parentheses. (C, F) Differences in the area under the concentration-response curve (dAUC) in aortic rings cultured in the presence of NS 398 (10−6 M) and furegrelate (FU, 10−3 M) under control (CT) conditions and after acute incubation with mercury HgCl2. *P<0.05 by Student’s t-test. Densitometric analysis of the western blot for cycloxxigenase-2 (COX-2) protein expression in aortic rings in control (CT) conditions or HgCl2. *P<0.05 by Student’s t-test. Number of animals used in parentheses. Representative blots are also shown.

Núbia Belem Lemos, et al. PLoS One. 2012;7(11):e49005.

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