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1.
Fig 1

Fig 1. From: Mycobacterium tuberculosis Region of Difference (RD) 2 Antigen Rv1985c and RD11 Antigen Rv3425 Have the Promising Potential To Distinguish Patients with Active Tuberculosis from M. bovis BCG-Vaccinated Individuals.

Amino acid sequences of 31 synthetic overlapping peptides covering the entire sequences of Rv1985c and Rv3425. Amino acid sequences are shown in single-letter code from the N terminus to the C terminus.

Sen Wang, et al. Clin Vaccine Immunol. 2013 January;20(1):69-76.
2.
Fig 2

Fig 2. From: Mycobacterium tuberculosis Region of Difference (RD) 2 Antigen Rv1985c and RD11 Antigen Rv3425 Have the Promising Potential To Distinguish Patients with Active Tuberculosis from M. bovis BCG-Vaccinated Individuals.

Epitope maps of Rv1985c and Rv3425 in the TB infection group (including the TB group and LTBI group) (A) and HC group (B). For each peptide, the recognition frequency is expressed as a percentage of the total number of subjects responding to that peptide. The cutoff value for a positive response was 40 pg/ml. The percentage of positive responses was divided into three groups according to the amount of IFN-γ released by antigen-specific T cells: low response (30 to 100 pg/ml; bar with horizontal stripes), moderate response (100 to 400 pg/ml; dotted bar), and high response (>400 pg/ml; crosshatched bar). Horizontal lines indicate the regions selected and pooled as diagnostic cocktails. Rv1985cpool1 contained P2 to P4, Rv1985cpool2 contained P8 to P10, Rv1985cpool3 contained P11 to P13, Rv1985cpool4 contained P15 and P16, and Rv3425pool contained P27 to P31.

Sen Wang, et al. Clin Vaccine Immunol. 2013 January;20(1):69-76.

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