Results: 3

1.
Figure 1

Figure 1. From: Late administration of surfactant replacement therapy increases surfactant protein-B content: a randomized pilot study.

Enrollment flow diagram for infants admitted to the nine study hospitals during the recruitment period, January 2008–October 2009.

Roberta L. Keller, et al. Pediatr Res. 2012 December;72(6):613-619.
2.
Figure 3

Figure 3. From: Late administration of surfactant replacement therapy increases surfactant protein-B content: a randomized pilot study.

Absolute change in surfactant parameters in infants treated with surfactant (n = 21) on day 1 vs. mean level of surfactant parameters on subsequent days prior to dosing (days 2–4). Surfactant protein-B (SP-B) content (%) normalized to total protein in surfactant: (a) vs. SP-B content r = 0.50, P = 0.02, and (b) surfactant recovery (μg phospholipid (PL)/μg tracheal aspirate protein): r = 0.05, P = 0.83.

Roberta L. Keller, et al. Pediatr Res. 2012 December;72(6):613-619.
3.
Figure 2

Figure 2. From: Late administration of surfactant replacement therapy increases surfactant protein-B content: a randomized pilot study.

Absolute change in surfactant parameters following study drug dosing (days 1–3). Data are median values for the Control (white bars, n = 43–47 from 20 infants) and Surfactant (black bars, n = 55–64 from 27 infants) groups. (a) Surfactant recovery, phospholipid (PL) normalized to total protein content of tracheal aspirate; (b) total protein in surfactant pellet as a percentage of PL; (c) surfactant protein-B (SP-B) content of surfactant pellet, normalized to PL; and (d) SP-B content normalized to total protein in surfactant pellet. P values are for comparison of the change between groups, *P = 0.04, **P ≤ 0.002.

Roberta L. Keller, et al. Pediatr Res. 2012 December;72(6):613-619.

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