Figure 1

Figure 1. From: MC1R variants predisposing to concomitant primary cutaneous melanoma in a monozygotic twin pair.

Phenotypic appearance of the twins and of their melanomas and identified germline MC1R variants. (A) Phenotypic features of twin-1 (left) and twin-2 (right); (B) Clinical image of twin-1’s melanoma located on the right anterior upper trunk; (C) Clinical image of twin-2’s melanoma excised from the right anterior lower trunk; (D) Heterozygous substitutions at codons 151 and 152 of the MC1R gene (NCBI accession NM_002386.3) identified in both twins.

Cristina Pellegrini, et al. BMC Med Genet. 2012;13:81-81.

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