Results: 5

1.
Figure 2

Figure 2. From: Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.

Univariate linear regressions between necroinflammatory degrees and liver shear wave velocity (SWV). Univariate linear regressions were both significant between serum alanine aminotransferase (ALT) levels and liver SWV (R2 = 0.074, P = .002) (A), and between ActiTest A scores and liver SWV (R2 = 0.198, P < .001) (B).

Sheng-Hung Chen, et al. BMC Gastroenterol. 2012;12:105-105.
2.
Figure 3

Figure 3. From: Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.

Box plot of liver stiffness corresponding to the METAVIR fibrosis (F) stages. The overall inter-group difference of liver shear wave velocity (SWV) among METAVIR F1 to F4 was significant (P < .001). Pair-wise comparisons also showed significant differences between groups: all P < .001, except P = .412 for F3 versus F4.

Sheng-Hung Chen, et al. BMC Gastroenterol. 2012;12:105-105.
3.
Figure 4

Figure 4. From: Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.

Receiver operating characteristic (ROC) curves to classify the METAVIR fibrosis stages. Two diagnostic modalities, liver shear wave velocity (SWV), and FibroTest (F score) were compared. P value: significance for comparisons of areas under ROC curves between using liver SWV and FibroTest.

Sheng-Hung Chen, et al. BMC Gastroenterol. 2012;12:105-105.
4.
Figure 1

Figure 1. From: Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.

Box plot of necroinflammatory degrees corresponding to the METAVIR fibrosis (F) stages. The Spearman’s rank correlation coefficients were 0.196 (P = .027) between serum alanine aminotransferase (ALT) levels and METAVIR F stages (A); 0.305 (P < .001) between ActiTest A scores and METAVIR F stages (B). Pair-wise comparisons of ActiTest A scores showed significant differences between groups F1, F2, and F3: all P < .005.

Sheng-Hung Chen, et al. BMC Gastroenterol. 2012;12:105-105.
5.
Figure 5

Figure 5. From: Effects of patient factors on noninvasive liver stiffness measurement using acoustic radiation force impulse elastography in patients with chronic hepatitis C.

Receiver operating characteristic (ROC) curves to classify the false positivity in METAVIR F1 to F3. Using alanine aminotransferase (ALT) levels (A) to discriminate the false positive in liver fibrosis evaluation using acoustic radiation force impulse elastography (n = 32) from the non false positive (n = 77) of the 109 patients with METAVIR F1, F2 and F3, the area under ROC curve (AUC) was 0.715 (standard error, SE, 0.053; 95% CI, 0.612-0.819; P < .001). The ALT level of 109.5 IU/L was the optimal cutoff value with a sensitivity of 56.3% and a specificity of 81.8%. Using the ActiTest A scores (B), the optimal cutoff was 0.35 (AUC, 0.736; SE, 0.051; 95% CI, 0.636-0.835; P < .001; sensitivity, 93.8%; specificity, 41.6%).

Sheng-Hung Chen, et al. BMC Gastroenterol. 2012;12:105-105.

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