Fig 1.

Fig 1. From: Diabetes, Metformin, and Breast Cancer in Postmenopausal Women.

Incidence of invasive breast cancers in the Women's Health Initiative. Cumulative hazard functions of invasive breast cancer that allow for the time-dependent exposure variables of diabetes status and metformin use.31 Cumulative hazard functions began 5 years after enrollment to ensure that adequate numbers of ultimate metformin users were receiving the drug. Hazard ratios (HRs) and 95% CIs from a multivariate-adjusted Cox proportional hazards analysis.

Rowan T. Chlebowski, et al. J Clin Oncol. 2012 August 10;30(23):2844-2852.

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