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Results: 2

1.
FIGURE 1

FIGURE 1. From: Gray matter density of auditory association cortex relates to knowledge of sound concepts in primary progressive aphasia.

A, Accuracy results for the lexical decision task. LvPPA participants performed significantly worse than healthy controls on Sound words but did not differ from healthy controls on the other word categories. LvPPA also performed significantly worse on Sound words relative to their own performance on Sight words and Manipulation words. B, Reduced gray matter density in lvPPA participants (shown in orange) overlaps with auditory association cortex (shown in white) as functionally defined by an auditory localizer from in a separate fMRI study of healthy participants.

Michael F. Bonner, et al. J Neurosci. ;32(23):7986-7991.
2.
FIGURE 2

FIGURE 2. From: Gray matter density of auditory association cortex relates to knowledge of sound concepts in primary progressive aphasia.

A, Reduced gray matter density in lvPPA (orange) affects regions of auditory association cortex (white) that were activated by the Sound word category in an fMRI study of healthy participants (blue). Note that the fMRI activation results (blue) represent a single cluster that is split in two along the superior temporal sulcus in this inflated cortical rendering. B, Slices showing overlap (green) of reduced gray matter density in lvPPA and fMRI activation for the Sound word category in healthy participants. C, Relationship between gray matter density and impaired performance on the Sound word category in lvPPA participants. This analysis was performed within the peak voxel of activation to Sound words from the fMRI study of healthy participants (MNI coordinates: −68, −32, 4). Similar findings are evident for a 10 mm sphere centered on this peak voxel.

Michael F. Bonner, et al. J Neurosci. ;32(23):7986-7991.

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