Results: 4

1.
Scheme 1

Scheme 1. From: Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging.

Procedure for chemical modification of PLGA polymers with nanocrystals.

Aneta J. Mieszawska, et al. Chem Commun (Camb). 2012 June 14;48(47):5835-5837.
2.
Fig. 2

Fig. 2. From: Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging.

Lipid-PLGA nanoparticles with QDs (A) TEM image and (B) absorbance and emission spectra; inset: lipid-PLGA nanoparticles under ambient light and UV illumination.

Aneta J. Mieszawska, et al. Chem Commun (Camb). 2012 June 14;48(47):5835-5837.
3.
Fig. 3

Fig. 3. From: Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging.

Results of in vitro experiments. (A) CT image and (B) fluorescent image of cell pellets, (C) TEM image of cells incubated with lipid-PLGA–AuNCs nanoparticles (arrows) and (D) confocal image of cells (nuclei in blue) incubated with lipid-PLGA–QDs nanoparticles (red).

Aneta J. Mieszawska, et al. Chem Commun (Camb). 2012 June 14;48(47):5835-5837.
4.
Fig. 1

Fig. 1. From: Engineering of lipid-coated PLGA nanoparticles with a tunable payload of diagnostically active nanocrystals for medical imaging.

TEM images of lipid-PLGA nanoparticles only (A), and with AuNCs ×1 (B), AuNCs ×2 (C), and AuNCs ×3 (D); all scale bars are 50 nm. (E) Lipid-PLGA nanoparticles with increasing amounts of AuNCs. (F) CT contrast obtained from lipid-PLGA nanoparticles with AuNCs compared to Isovue and water at 140 kV and 250 mA (scale in Hounsfield units).

Aneta J. Mieszawska, et al. Chem Commun (Camb). 2012 June 14;48(47):5835-5837.

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