Results: 5

1.
Fig. (4)

Fig. (4). From: Injection of Human Bone Marrow and Mononuclear Cell Extract into Infarcted Mouse Hearts Results in Functional Improvement.

Human BMC and MNC extracts result in smaller infarct scar sizes compared to controls.

Franca S Angeli, et al. Open Cardiovasc Med J. 2012;6:38-43.
2.
Fig. (5)

Fig. (5). From: Injection of Human Bone Marrow and Mononuclear Cell Extract into Infarcted Mouse Hearts Results in Functional Improvement.

HMNC extract and hBMC extract had more vessels in the border zone than the control group but only the hBMC group reached statistical significance.

Franca S Angeli, et al. Open Cardiovasc Med J. 2012;6:38-43.
3.
Fig. (1)

Fig. (1). From: Injection of Human Bone Marrow and Mononuclear Cell Extract into Infarcted Mouse Hearts Results in Functional Improvement.

Echocardiographic changes in the left ventricular ejection fraction (LVEF) from day 2 to day 28 post-MI. Both human BMC and MNC extracts significantly improved % LVEF change compared with control which showed continued deterioration of the LVEF post-MI.

Franca S Angeli, et al. Open Cardiovasc Med J. 2012;6:38-43.
4.
Fig. (2)

Fig. (2). From: Injection of Human Bone Marrow and Mononuclear Cell Extract into Infarcted Mouse Hearts Results in Functional Improvement.

This figure demonstrates representative echocardiograms of the various groups: The left image shows an example of a remodeled heart from the control group with LV dilation and apical aneurysm (red arrow). Right upper panel is an example of a heart treated with hBMC-extract and the right lower panel shows an example of an animal treated with hMNCs-extract. Both of these demonstrate limitation of LV dilation and less geometric changes compared to the control group.

Franca S Angeli, et al. Open Cardiovasc Med J. 2012;6:38-43.
5.
Fig. (3)

Fig. (3). From: Injection of Human Bone Marrow and Mononuclear Cell Extract into Infarcted Mouse Hearts Results in Functional Improvement.

Changes in left ventricular volumes over time following myocardial infarction by echocardiography. (A) End systolic volume and (B) end diastolic volume at day 2 and at 4 weeks post myocardial infarction. Data are shown as mean ± SD. At day 2, pre-MI, all three groups have similar ESV and EDV values. hMNC extract was associated with significantly smaller volumes at day 28 compared to the control group and there was a trend towards smaller volumes with the hBMC extract but this did not reach statistical significance.

Franca S Angeli, et al. Open Cardiovasc Med J. 2012;6:38-43.

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