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Results: 5

1.
Fig 3

Fig 3. From: Identical Consensus Sequence and Conserved Genomic Polymorphism of Hepatitis E Virus during Controlled Interspecies Transmission.

Plot of the number of sequencing errors versus the number of nucleotides mapped over conserved genes of host species and bacteria from our HEV samples. The black line represents the linear regression resulting in an error rate of 0.28%.

Jerome Bouquet, et al. J Virol. 2012 June;86(11):6238-6245.
2.
Fig 4

Fig 4. From: Identical Consensus Sequence and Conserved Genomic Polymorphism of Hepatitis E Virus during Controlled Interspecies Transmission.

SNPs along the HEV genome. A schematic representation of the HEV genome is aligned at the top of the figure (see the legend of Fig. 2). Bars indicate the percentage of validated SNPs along the HEV genome sequenced from the human sample (A), the feces of pigs (B), and the bile of pigs (C). Black arrows indicate the position of SNPs shared by the three samples.

Jerome Bouquet, et al. J Virol. 2012 June;86(11):6238-6245.
3.
Fig 5

Fig 5. From: Identical Consensus Sequence and Conserved Genomic Polymorphism of Hepatitis E Virus during Controlled Interspecies Transmission.

Viral intrahost nucleotide diversity (π) of viruses. Values of π are displayed as percentages on a logarithmic number line for HEV alongside the West Nile virus (WNV), human immunodeficiency virus (HIV), and hepatitis C virus (HCV) (15, 33, 34).

Jerome Bouquet, et al. J Virol. 2012 June;86(11):6238-6245.
4.
Fig 2

Fig 2. From: Identical Consensus Sequence and Conserved Genomic Polymorphism of Hepatitis E Virus during Controlled Interspecies Transmission.

Coverage of the HEV genome by high-throughput sequencing. A schematic representation of the HEV genome is shown at the top of the figure. ORFs are drawn to scale, and the UTR, the hypervariable region (HVR), and the region coding for the RNA polymerase (RP) are highlighted. Numbers of reads are projected along the genomic position. Black line, bile samples pooled from the two pigs; plain gray line, feces sample pooled from the two pigs; dotted gray line, human sample.

Jerome Bouquet, et al. J Virol. 2012 June;86(11):6238-6245.
5.
Fig 1

Fig 1. From: Identical Consensus Sequence and Conserved Genomic Polymorphism of Hepatitis E Virus during Controlled Interspecies Transmission.

Experimental infection of two pigs with human HEV. The HEV load of initial human fecal sample inoculated to pigs is plotted as a black square. Excretion of the virus in the feces of pigs is plotted as white squares for pig 1 and as gray squares for pig 2. The HEV load in the bile is plotted as white dots for pig 1 and as gray dots for pig 2. The presence of anti-HEV IgG in serum is indicated by black diamonds. Samples used in high-throughput sequencing are boxed in black. Times of inoculation, surgery, and euthanasia are indicated on the axis for days postinfection.

Jerome Bouquet, et al. J Virol. 2012 June;86(11):6238-6245.

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