Display Settings:

Items per page

Results: 6

2.
Figure 1

Figure 1. Cumulative incidence of AGA antibodies.. From: Proof of Concept of Microbiome-Metabolome Analysis and Delayed Gluten Exposure on Celiac Disease Autoimmunity in Genetically At-Risk Infants.

Percent of AGA positive subjects enrolled in the study in each intervention group. * denotes time of gluten introduction, red, group B and blue, group A.

Maria Sellitto, et al. PLoS One. 2012;7(3):e33387.
3.
Figure 6

Figure 6. 1H-NMR metabolomics analysis.. From: Proof of Concept of Microbiome-Metabolome Analysis and Delayed Gluten Exposure on Celiac Disease Autoimmunity in Genetically At-Risk Infants.

A. PCA analysis of metabolomic profiles (A). Relative concentration of major metabolites measured from stool NMR profiles in selected subjects over the 24-month study period (B–F). B. Succinate; C. Acetate; D. Lactate; E. Butyrate and F. Propionate. The chemical shift (ppm) value of each metabolite is indicated above each panel.

Maria Sellitto, et al. PLoS One. 2012;7(3):e33387.
4.
Figure 4

Figure 4. Heatmap of relative abundance of bacterial phylum of longitudinal samples from DQ2+/DQ8+ infants analyzed in this study and those of Palmer et al. [28] (D), Color keys are indicated on the upper right corner.. From: Proof of Concept of Microbiome-Metabolome Analysis and Delayed Gluten Exposure on Celiac Disease Autoimmunity in Genetically At-Risk Infants.

A. Complete linkage clustering based on the phylum composition and abundance of GI microbiota. B. Color depicts the study and intervention group of the samples. C. Colors depict the time point at which the samples were collected. Time points D and E were omitted as no corresponding samples were collected in the Palmer et al. study [28].

Maria Sellitto, et al. PLoS One. 2012;7(3):e33387.
5.
Figure 5

Figure 5. Principal Coordinate Analysis (PCoA) of unweighted UniFrac distances between samples.. From: Proof of Concept of Microbiome-Metabolome Analysis and Delayed Gluten Exposure on Celiac Disease Autoimmunity in Genetically At-Risk Infants.

A. Samples are colored by time points, red, 7 d and 30 d, green, 6 m and 8 m, light blue, 10 m and 12 m, dark blue, 18 m and 24 m. B. Samples are colored by intervention groups. Group A: red, Group B: green. Blue: 7 d and 30 d time points prior to diet intervention. A and B: Gold, adult controls: subject 34 gluten-free diet for over 24 weeks and HLA DQ2/8+; subject 67 HLA DQ2/8−; subject 103 HLA DQ2/8+; subject 86; diagnosed with CD and HLA DQ2/8+.

Maria Sellitto, et al. PLoS One. 2012;7(3):e33387.
6.
Figure 2

Figure 2. Heatmaps of relative abundance of bacterial phylum in the GI microbiota of samples collected longitudinally from 7 d to 24 months of age in DQ2+/DQ8+ infants (color key is indicated on the right).. From: Proof of Concept of Microbiome-Metabolome Analysis and Delayed Gluten Exposure on Celiac Disease Autoimmunity in Genetically At-Risk Infants.

A. Samples are grouped by subjects ID and intervention groups. B. Samples are grouped by timepoints. Red bars indicate samples from subjects in intervention group B. Missing data point are indicated with a white vertical line. Stool samples collected from adult subjects that were processed in parallel are included for comparison (from left to right): subject 69: gluten-free diet for more than 24 weeks and HLA DQ2/8+; subject 103: HLA DQ2/8+, subject 67 HLA DQ2/8−; subject 86: diagnosed with CD and HLA DQ2/8+; subject 34: gluten-free diet for more than 24 months and HLA DQ2/8+; subject 36: HLA DQ2/8−; subject 6: HLA DQ2/8+; subject 49: HLA DQ2/8−.

Maria Sellitto, et al. PLoS One. 2012;7(3):e33387.

Display Settings:

Items per page

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk