Results: 2

1.
Fig 1

Fig 1. From: Performance of the Novel Qiagen artus QS-RGQ Viral Load Assays Compared to That of the Abbott RealTime System with Genetically Diversified HIV and Hepatitis C Virus Plasma Specimens.

Correlation of viral loads as determined by Abbott RealTime and Qiagen artus QS-RGQ assays for HIV and HCV. Panels A and B show HIV and HCV reference panel specimens and panels C and D HIV and HCV clinical plasma specimens, respectively. In panel A, non-group M reference panel specimens were excluded because the Qiagen assay is not licensed for those. In panel C, three HIV specimens (one HIV CRF AG specimen quantifiable only by Abbott at 5.07 Log10 IU/ml and two subtype B specimens quantifiable only by Qiagen at 3.09 and 3.80 Log10 IU/ml, respectively) that were positive in one assay but repeatedly negative in the other assay were excluded. Specimen type, the number of samples (n), and Pearson's bivariate correlation coefficient (r) are given in the bottom right corner of each panel.

Jan Felix Drexler, et al. J Clin Microbiol. 2012 June;50(6):2114-2117.
2.
Fig 2

Fig 2. From: Performance of the Novel Qiagen artus QS-RGQ Viral Load Assays Compared to That of the Abbott RealTime System with Genetically Diversified HIV and Hepatitis C Virus Plasma Specimens.

Quantitative deviations between Abbott RealTime and Qiagen artus QS-RGQ viral load assays for HIV and HCV. Each box shows the median, interquartile range (box length, containing 50% of data), and whiskers, representing datum points within 1.5-fold of the interquartile range. Datum points beyond the whisker range are considered outliers, and extreme values (>3-fold beyond the interquartile range) are marked as circles and asterisks, respectively. Dashed lines on the y axis indicate 0.5 Log10 deviations from zero. (A and B) HIV subtypes/circulating recombinant forms (CRF) (A) and HCV genotypes (B) are indicated below the x axis with the numbers of samples tested per type (combined numbers from reference panel members and clinical specimens). For graphical reasons, HIV subtype F and circulating recombinant forms (CRF) containing F at any genomic position (one F, one BF, and three DF specimens) were summarized as F/BF/DF. The same was done for multiple recombinant CRF (one CRF06, two CRF09, and one CRF11 specimen), termed CPX. (C) Deviations between viral load determinations for n = 10 HCV genotype reference panel members (genotypes 1a, 1b, 2a, 2b, 2c, 2i, 3a, 4, 5a, and 6; University of Essen, Germany) by the Qiagen and Abbott assays and an additional three viral load assays are shown. bDNA, Bayer Versant bDNA version 3.0; Amplicor, Roche COBAS Amplicor version 2.0; X-tail, X-tail real-time RT-PCR.

Jan Felix Drexler, et al. J Clin Microbiol. 2012 June;50(6):2114-2117.

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