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Results: 6

1.
Fig. 5

Fig. 5. From: Apolipoprotein E Genotype-Dependent Paradoxical Short-Term Effects of 56Fe Irradiation on the Brain.

Representative images of DHE oxidation of sham-irradiated (A, C, and E) and irradiated (B, D, and F) mice 16 min after exposure to DHE.

Gwendolen E. Haley, et al. Int J Radiat Oncol Biol Phys. ;84(3):793-799.
2.
Fig. 3

Fig. 3. From: Apolipoprotein E Genotype-Dependent Paradoxical Short-Term Effects of 56Fe Irradiation on the Brain.

(A) First (A), second (B), and third (C) water maze probe trials. n = 8 mice/genotype/treatment. *, p < 0.05; **, p < 0.01.

Gwendolen E. Haley, et al. Int J Radiat Oncol Biol Phys. ;84(3):793-799.
3.
Fig. 1

Fig. 1. From: Apolipoprotein E Genotype-Dependent Paradoxical Short-Term Effects of 56Fe Irradiation on the Brain.

Novel object recognition of sham-irradiated and irradiated mice. The total time (sec) (A) and percentage of time exploring the novel object (B) are shown. n = 8 mice/genotype/treatment. ***, p < 0.001 versus familiar object.

Gwendolen E. Haley, et al. Int J Radiat Oncol Biol Phys. ;84(3):793-799.
4.
Fig. 6

Fig. 6. From: Apolipoprotein E Genotype-Dependent Paradoxical Short-Term Effects of 56Fe Irradiation on the Brain.

(A) Diagram of hippocampal regions used for DHE analysis. (B) ApoE isoform-dependent effects of irradiation on hippocampal superoxide levels assessed by fluorescent imaging of DHE oxidation. *, p < 0.05. n = 3 to 4 slices per genotype per treatment and region.

Gwendolen E. Haley, et al. Int J Radiat Oncol Biol Phys. ;84(3):793-799.
5.
Fig. 4

Fig. 4. From: Apolipoprotein E Genotype-Dependent Paradoxical Short-Term Effects of 56Fe Irradiation on the Brain.

Levels of brain apoE (A), 3-NT (B), EC-SOD (C), and CuZnSOD (D) in sham-irradiated and irradiated mice. The 125-kDa 3-NT, 75-kDa CuZnSOD, and 19-kDa EC-SOD bands were used for quantification. The gel lanes match the order of the bar graph. β-Actin was the loading control (not shown). *, p < 0.05; **, p = 0.01 compared to apoE2 irradiated mice.

Gwendolen E. Haley, et al. Int J Radiat Oncol Biol Phys. ;84(3):793-799.
6.
Fig. 2

Fig. 2. From: Apolipoprotein E Genotype-Dependent Paradoxical Short-Term Effects of 56Fe Irradiation on the Brain.

(A) Contextual and cued fear conditioning of sham-irradiated and irradiated mice. (A) Baseline motion index. (B) Motion index during the shock. (C) Contextual fear conditioning. (D) Cued fear conditioning task. n = 8 mice/genotype/treatment. ***, p < 0.001 compared to apoE3 and apoE4 mice; *, p < 0.05 versus the time prior to the tone (pre-tone) during the training was paired with the shock.

Gwendolen E. Haley, et al. Int J Radiat Oncol Biol Phys. ;84(3):793-799.

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