We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Results: 5

1.
Figure 4

Figure 4. From: Characterizing brain oxygen metabolism in patients with multiple sclerosis with T2-relaxation-under-spin-tagging MRI.

Box-plot representation of Yv (n=30) (A) and cerebral metabolic rate of oxygen (CMRO2) (n=12) (B) in control and multiple sclerosis (MS) groups, demonstrating significantly higher Yv (%) (mean±s.d.: 65.9±5.1 versus 60.2±4.0; P=0.001) and lower CMRO2 (μmol per 100 g per minute) (138.8±35.4 versus 180.2±24.8, P=0.003) in patients than controls.

Yulin Ge, et al. J Cereb Blood Flow Metab. 2012 March;32(3):403-412.
2.
Figure 1

Figure 1. From: Characterizing brain oxygen metabolism in patients with multiple sclerosis with T2-relaxation-under-spin-tagging MRI.

The placement of labeling slab (purple) of T2-relaxation-under-spin-tagging (TRUST) sequence is above the actual imaging slice (green) to obtain draining venous blood signal measured in the lower superior sagittal sinus. Labeling slab thickness 50 mm, and gap 25 mm. The color reproduction of this figure is available on the Journal of Cerebral Blood Flow and Metabolism journal online.

Yulin Ge, et al. J Cereb Blood Flow Metab. 2012 March;32(3):403-412.
3.
Figure 2

Figure 2. From: Characterizing brain oxygen metabolism in patients with multiple sclerosis with T2-relaxation-under-spin-tagging MRI.

T2-relaxation-under-spin-tagging (TRUST) magnetic resonance imaging (MRI) images in which the venous blood is either magnetically labeled (Label, middle row) or unlabeled (Control, top row). Each type of image is acquired at four different T2-weightings, denoted by the effective echo time (eTE). The bottom row is the subtracted image (control-label). The red rectangle indicates the region of interest containing the draining blood signal in the lower portion of superior sagittal sinus.

Yulin Ge, et al. J Cereb Blood Flow Metab. 2012 March;32(3):403-412.
4.
Figure 3

Figure 3. From: Characterizing brain oxygen metabolism in patients with multiple sclerosis with T2-relaxation-under-spin-tagging MRI.

Global cerebral blood flow (CBF) was measured with phase-contrast magnetic resonance imaging (MRI) magnitude (A) and phase (B) images and the positioning of phase-contrast scan was based on a 2D time-of-flight (TOF) angiogram including coronal (C) and sagittal projections (D) and the imaging slice was just above the bifurcation of carotid arteries (dash lines). The quantification of global CBF used all four arteries including bilateral internal carotid (thick arrows) and vertebral (thin arrows) arteries and applied their masks onto a velocity map.

Yulin Ge, et al. J Cereb Blood Flow Metab. 2012 March;32(3):403-412.
5.
Figure 5

Figure 5. From: Characterizing brain oxygen metabolism in patients with multiple sclerosis with T2-relaxation-under-spin-tagging MRI.

Relationship between Yv and expanded disability status scale (EDSS) (A) and lesion volume (B), and between cerebral metabolic rate of oxygen (CMRO2) and EDSS (C) and lesion volume (D) in patients with multiple sclerosis (MS) patients. A significant positive correlation was observed between Yv and EDSS (r=0.54, P=0.002) (A) and between Yv and lesion volume (cm3) (r=0.40, P=0.03) (B). In contrast, there was significant negative correlation between CMRO2 and EDSS (r=−0.61, P=0.03) (C) and between CMRO2 and lesion volume (r=−0.74, P=0.005) (D) in patients with relapsing-remitting MS, suggesting that patients with a higher venous oxygenation level (Yv) or lower oxygen consumption tend to have higher clinical disability and lesion load.

Yulin Ge, et al. J Cereb Blood Flow Metab. 2012 March;32(3):403-412.

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk