Results: 5

Figure 5

Figure 5. Discovered Bayesian Network for the full set of GBM (A) and the Proneural subtype (B).. From: Expression Signature of IFN/STAT1 Signaling Genes Predicts Poor Survival Outcome in Glioblastoma Multiforme in a Subtype-Specific Manner.

Growth-shrink algorithm was used and 80% bootstrap support for presence of edges and 50% bootstrap support for edge direction were required for the full sample (A), and 50% each were required for the Proneural subtype (B). With the more stringent criteria for the Proneural subtype (80% bootstrap support for edge presence) the OAS1->MX1 and ISG15->IFIT1 edges were discovered.

Christine W. Duarte, et al. PLoS One. 2012;7(1):e29653.

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