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Results: 3

1.
Figure 3

Figure 3. Cortical regions of gray matter volume decreases in the deletion group compared to the UPD group. From: The Neuroanatomy of Genetic Subtype Differences in Prader-Willi Syndrome.

Gray matter regions are displayed on a 3-D surface-rendered standard brain. The top row shows a frontal view on the left and posterior view on the right of the cortex, demonstrating posterior parietal gray matter decreases. The middle row shows left and right outer views of the cortex showing right temporal and left parietal decreases in gray matter volume. The bottom shows a ventral view on the left and a dorsal view on the right. Results are displayed at p<.05 FWE corrected, Z score range shown on the color bar.

Robyn A. Honea, et al. Am J Med Genet B Neuropsychiatr Genet. ;159B(2):243-253.
2.
Figure 2

Figure 2. Cortical regions from genetic subtype comparison of HWC to the deletion group (A, C) and the UPD group (B, D). From: The Neuroanatomy of Genetic Subtype Differences in Prader-Willi Syndrome.

Gray matter regions are displayed on a 3-D surface-rendered standard brain (A, B) and white matter regions are displayed on a 2-D standard brain (C,D). A. The top row of section A shows left and right lateral views of gray matter volume decreases in DEL subjects compared to HWC, highlighting the temporal and frontal decreases in this group. The bottom row of section A shows ventral and dorsal views, displaying decreases in hippocampal and prefrontal gray matter. C. Row C shows sagittal and axial views of white matter volume decreases in HWC subjects. B. The top row of section B shows left and right lateral views of gray matter volume decreases in UPD subjects compared to HWC. The bottom row of section B shows ventral and dorsal views, displaying decreases in hippocampal and orbitofrontal cortical gray matter. D. Row D shows sagittal and axial views of white matter volume decreases in UPD subjects. Results are displayed at p<.05 FWE corrected, Z score range shown on the color bar.

Robyn A. Honea, et al. Am J Med Genet B Neuropsychiatr Genet. ;159B(2):243-253.
3.
Figure 1

Figure 1. Cortical regions show smaller gray and white matter volume in the PWS group compared to healthy-weight controls. From: The Neuroanatomy of Genetic Subtype Differences in Prader-Willi Syndrome.

Gray matter regions are displayed on a 3-D surface-rendered standard brain and white matter regions are displayed on a 2-D standard brain. A. The top row of section A shows a frontal view on the left and posterior view on the right of the cortex, demonstrating bilateral frontal gray matter decreases. The middle row of section A shows left and right outer views of the cortex showing the temporal and frontal decreases in gray matter volume. The bottom row of section A shows a ventral view on the left and a dorsal view on the right, demonstrating orbitofrontal and medial temporal (limbic) decreases in gray matter volume. B. Section B shows sagittal and axial views of white matter volume decreases in PWS subjects, highlighting the midbrain, brainstem, thalamic and corpus callosum white matter decreases (all part of a large cluster) on the left, and on the right showing decreases in the inferior frontal and precentral cortices. Results are displayed at p<.05 FWE corrected, Z score range shown on the color bar.

Robyn A. Honea, et al. Am J Med Genet B Neuropsychiatr Genet. ;159B(2):243-253.

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