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FIGURE 1.

FIGURE 1. From: Alcohol consumption and the risk of colon cancer by family history of colorectal cancer1234.

Pooled multivariate RR of colon cancer according to cumulative alcohol intake and family history of colorectal cancer. RR was stratified by age in months at the start of follow-up and calendar year of the current questionnaire cycle and was simultaneously adjusted for the following factors: pack-years of smoking before age 30 y (never smoker; 1–4, 5–10, or ≥11 y of smoking), BMI (in kg/m2; <23, 23 to <25, 25 to <30, 30 to <35, or ≥35), history of endoscopy (yes or no), use of aspirin (never; past; current use of 1–2, 3–5, 6–14, or ≥15 tablets/wk), and intakes of energy (continuous), calcium (continuous), folate (<250, 250 to <400, 400 to <600, 600 to <800, or ≥800 μg/d), and red meat (quintiles). In the NHS, information on menopausal status and use of postmenopausal hormone (premenopausal, never, past, or current) were also adjusted for. The number of cases in each category was 268 for 0 g alcohol/d and no family history, 846 for 0.1–14.9 g alcohol/d and no family history, 152 for 15 to <30 g alcohol/d and no family history, 111 for ≥30 g alcohol/d and no family history, 71 for 0 g alcohol/d and family history, 260 for 0.1–14.9 g alcohol/d and family history, 49 for 15 to <30 g alcohol/d and family history, and 44 for ≥30 g alcohol/d and family history. *RR was significant. NHS, Nurses’ Health Study.

Eunyoung Cho, et al. Am J Clin Nutr. 2012 February;95(2):413-419.

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