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Results: 4

1.
Figure 4

Figure 4. From: Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease.

Genome wide eQTL mapping of Laptm4b transcript in Treg and Th cells. (A) eQTL map for Laptm4b (probeset 1416148_at in Tregs and (B) in Th, respectively. See figure 3 for explanation of labels.

Rudi Alberts, et al. BMC Genomics. 2011;12:610-610.
2.
Figure 1

Figure 1. From: Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease.

Genome-wide graph of cis- and trans-eQTLs in Treg cells. The positions of the eQTLs are plotted against the locations of the corresponding transcript along the genome. Cis-regulated genes are located along the diagonal, all other dots represent trans-regulated genes. The significance level of each QTL is indicated by the color. FDR = 0.3.

Rudi Alberts, et al. BMC Genomics. 2011;12:610-610.
3.
Figure 2

Figure 2. From: Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease.

Genome-wide graph of cis- and trans-eQTLs in Th cells. The positions of the eQTLs are plotted against the locations of the corresponding transcript along the genome. Cis-regulated genes are located at the diagonal, all other dots represent trans-regulated genes. The significance level of each QTL is indicated by the color. FDR = 0.3.

Rudi Alberts, et al. BMC Genomics. 2011;12:610-610.
4.
Figure 3

Figure 3. From: Expression QTL mapping in regulatory and helper T cells from the BXD family of strains reveals novel cell-specific genes, gene-gene interactions and candidate genes for auto-immune disease.

Genome wide eQTL mapping of Stx11 transcript in Treg and Th cells. (A) eQTL map for Stx11 (probeset 1453228_at) in Tregs and (B) in Th, respectively. The numbers at the top are chromosomes, and positions at the bottom are given in megabases along the chromosome. The blue line represents the significance level of the QTL expressed as LRS score (likelihood ratio statistic). A positive additive coefficient (green line) indicates that DBA/2J alleles increased trait values. A negative additive coefficient (red line) indicates that C57BL/6J alleles increased trait values. The two horizontal lines mark the genome-wide significance levels at p < 0.05 (red line) and p < 0.37 (gray line). A blue triangle marks the position of the gene.

Rudi Alberts, et al. BMC Genomics. 2011;12:610-610.

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