Results: 4

1.
Figure 2

Figure 2. From: Whole Blood Flow Cytometry Measurements of In Vivo Platelet Activation in Critically-Ill Patients are Influenced by Variability in Blood Sampling Techniques.

PAC-1 binding and P-SEL expression does not differ between (A) baseline or (B) TRAP-activated arterial and venous whole blood in critically-ill patients (p=NS all comparisons in multivariate comparisons after controlling for APACHE II score, processing time, ICU day, age, gender, and platelet counts).

Matthew T. Rondina, et al. Thromb Res. ;129(6):729-735.
2.
Figure 4

Figure 4. From: Whole Blood Flow Cytometry Measurements of In Vivo Platelet Activation in Critically-Ill Patients are Influenced by Variability in Blood Sampling Techniques.

Levels of PMA correlate with the number of circulating platelets. Whole blood was left alone (baseline, Panel A) or stimulated with TRAP (Panel B) for 15 minutes (*p<0.05 for trend in multivariate analyses after controlling for APACHE II score, age, gender, ICU day, vascular sampling site, and processing time).

Matthew T. Rondina, et al. Thromb Res. ;129(6):729-735.
3.
Figure 3

Figure 3. From: Whole Blood Flow Cytometry Measurements of In Vivo Platelet Activation in Critically-Ill Patients are Influenced by Variability in Blood Sampling Techniques.

Delayed processing times were associated with increased levels of platelet-monocyte aggregates (PMA), but not PAC-1 binding or P-SEL expression. Whole blood was left alone (baseline, Panel A) or stimulated with TRAP (Panel B) for 15 minutes. (*p<0.05 for trend in multivariate comparisons after controlling for APACHE II score, age, gender, vascular sampling site, ICU day, and platelet counts).

Matthew T. Rondina, et al. Thromb Res. ;129(6):729-735.
4.
Figure 1

Figure 1. From: Whole Blood Flow Cytometry Measurements of In Vivo Platelet Activation in Critically-Ill Patients are Influenced by Variability in Blood Sampling Techniques.

Platelet-monocyte aggregates are higher in arterial whole blood from critically-ill patients. Platelet-monocyte aggregates were assessed in (A) baseline (e.g. unstimulated) or (B) TRAP-activated arterial or venous whole blood. Panel C shows a representative flow cytometric analysis of unstimulated and TRAP-activated platelet-monocyte aggregates measured in arterial (left) and venous (right) whole blood samples (*p<0.05 versus venous whole blood samples in multivariate comparisons after controlling for APACHE II score, processing time, ICU day, age, gender, and platelet count).

Matthew T. Rondina, et al. Thromb Res. ;129(6):729-735.

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk