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Results: 5

1.
Figure 2

Figure 2. From: Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.

Semilogarithmic plot of mean plasma concentration–time data of XN obtained from Sprague Dawley rats (n = 12) given a single intravenous dose of 1.86 mg / kg BW.

LeeCole Legette, et al. Mol Nutr Food Res. 2012 March;56(3):466-474.
2.
Figure 4

Figure 4. From: Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.

Semilogarithmic plot of mean plasma concentration–time data of IX obtained from Sprague Dawley rats (n = 12/dose) given a single oral dose of XN (1.86, 5.64 or 16.9 mg / kg BW).

LeeCole Legette, et al. Mol Nutr Food Res. 2012 March;56(3):466-474.
3.
Figure 1

Figure 1. From: Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.

Metabolic conversion of XN into desmethylxanthohumol (DMX) and 6- and 8-prenylnaringenin (6PN and 8PN). XN is spontaneously converted into isoxanthohumol (IX) by intramolecular Michael addition. 6PN is formed from DMX. 8PN can be formed from DMX or from IX by CYP-mediated demethylation [28, 31].

LeeCole Legette, et al. Mol Nutr Food Res. 2012 March;56(3):466-474.
4.
Figure 3

Figure 3. From: Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.

Semilogarithmic plot of mean plasma concentration–time data of XN obtained from Sprague Dawley rats (n = 12/dose) given a single oral dose of XN (1.86, 5.64 or 16.9 mg / kg BW).

LeeCole Legette, et al. Mol Nutr Food Res. 2012 March;56(3):466-474.
5.
Figure 5

Figure 5. From: Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.

Semilogarithmic plot of mean plasma concentration–time data of 8PN obtained from Sprague Dawley rats (n = 12/dose) given a single oral dose of XN (1.86, 5.64 or 16.9 mg / kg BW).

LeeCole Legette, et al. Mol Nutr Food Res. 2012 March;56(3):466-474.

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