FIGURE 1. From: Vitamin D deficiency and age at menarche: a prospective study123.

Cumulative probabilities of reaching menarche according to plasma concentrations of 25(OH)D in 242 Colombian school-age girls. The proportions of girls who reached menarche during a median of 30 mo of follow-up in groups with 25(OH)D concentrations of <50 nmol/L (deficient), ≥50 and <75 nmol/L, or ≥75 nmol/L (sufficient) were 57% (n = 16 of 28), 40% (n = 49 of 124), and 23% (n = 21 of 90), respectively (P = 0.0004, Cochrane-Armitage test for trend). 25(OH)D, 25-hydroxyvitamin D.

Eduardo Villamor, et al. Am J Clin Nutr. 2011 October;94(4):1020-1025.

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