We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

Results: 3

1.
Figure 3

Figure 3. Estimate gray matter under clusters of significance (Figure 2). From: Fronto-parietal hypo-activation during working memory independent of structural abnormalities: Conjoint fMRI and sMRI analyses in adolescent offspring of schizophrenia patients.

Volumetric estimates of gray matter in clusters of maximal difference. Mean estimates of gray matter volume under the significant clusters of interest (depicted on dorsal surface views in the center are depicted. See results for statistical analyses and effect sizes on the main effects. Error bars are ± s.d.

Vaibhav A. Diwadkar, et al. Neuroimage. ;58(1):234-241.
2.
Figure 2

Figure 2. Contrast Differences, HC > HR-S in parietal and frontal cortex. From: Fronto-parietal hypo-activation during working memory independent of structural abnormalities: Conjoint fMRI and sMRI analyses in adolescent offspring of schizophrenia patients.

a) Bilateral Parietal Hypo-activity (pc<.01) during working memory in HR-S. Significantly reduced activity in bilateral superior parietal cortex (BA 7 & 40) during the 2 back task in HR-S relative to controls is projected on dorsal, medial and lateral surfaces of the brain. b) Dorsal Prefrontal Hypoactivity in HR-S. Significantly reduced activity (pc<.01) in left dorso-lateral prefrontal cortex during the 2 back task in HR-S relative to controls is projected on dorsal and lateral. Peak statistics and cluster extents are shown in the results.

Vaibhav A. Diwadkar, et al. Neuroimage. ;58(1):234-241.
3.
Figure 1

Figure 1. Main effect of group (HR-S, HC). From: Fronto-parietal hypo-activation during working memory independent of structural abnormalities: Conjoint fMRI and sMRI analyses in adolescent offspring of schizophrenia patients.

Whole brain analyses of activation differences between HRS-S and HC depict a main effect of group in the dorsal prefrontal cortex (dPFC), superior parietal cortex (SP), cingulate gyrus (CingG), superior temporal gyrus (STG) and middle temporal gyrus (MTG; See Table 2 for statistics). The results are largely consistent with the limited fMRI studies in clinical risk populations within the schizophrenia diathesis (see text for references).

Vaibhav A. Diwadkar, et al. Neuroimage. ;58(1):234-241.

Supplemental Content

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk