Results: 2

1.
Figure 1

Figure 1. From: Association of PPP2CA polymorphisms with SLE susceptibility in multiple ethnic groups.

PPP2CA gene structure with tested SNPs and haplotype blocks in HA, EA, Asian and AA patients. A. The −log10 base of allelic p value for each SNP. B. PPP2CA gene structure with tested SNPs. Two SNPs (rs7704116 and rs10491322) that showed consistently strong association with SLE across Asian, EA and HA are marked with frame. C. Haplotype blocks based on 18 tested SNPs in HA, EA, Asian and AA SLE patients.

Wenfeng Tan, et al. Arthritis Rheum. ;63(9):2755-2763.
2.
Figure 2

Figure 2. From: Association of PPP2CA polymorphisms with SLE susceptibility in multiple ethnic groups.

Association of PPP2CA genotypes with mRNA expression levels. Relative mRNA expression levels of PPP2CA in isolated T cells from SLE and healthy controls (HC) with the AG or GG genotype at rs7704116 (AG = 8 vs. GG = 21 in SLE and AG = 8 vs. GG = 9 in healthy controls) were determined by real-time PCR and normalized to GAPDH. Relative mRNA expression levels were log 10 transformed to normalize its distribution. The results represent the mean±SD of four independent experiments. None of the subjects were homozygous for the minor A allele.

Wenfeng Tan, et al. Arthritis Rheum. ;63(9):2755-2763.

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