Results: 2

1.
Figure 1

Figure 1. From: Chromosomal Copy Number Alterations are Associated with Tumor Response to Chemoradiation in Locally Advanced Rectal Cancer.

Overall frequency of copy number alterations (CNAs) detected by oligonucleotide array-based comparative genomic hybridization (aCGH) in 95 rectal cancer patients. The most common alterations were gains in chromosomes 20, 13, 8 and 7 and losses in chromosomes 18, 8, 17 and 4.

Zhenbin Chen, et al. Genes Chromosomes Cancer. ;50(9):689-699.
2.

Figure 2. From: Chromosomal Copy Number Alterations are Associated with Tumor Response to Chemoradiation in Locally Advanced Rectal Cancer.

a: 58 probes were used to build a predictive model using Support Vector Machine (SVM) to predict pathologic complete response (pCR). Sample identification - Red: Loss; Green: Gain; Yellow: pCR; Blue: Non-pCR.
b: Receiver-Operator Characteristics (ROC) curve using the true positive rate and false positive rate to evaluate the prediction ability of pathologic complete response (pCR) using 58 probes selected from significant discriminated genomic aberrant regions between pCR and non-pCR patients. The area under the curve (AUC) value for the performance of the prediction is 0.96.

Zhenbin Chen, et al. Genes Chromosomes Cancer. ;50(9):689-699.

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